KEMRI Journals & Articles: Recent submissions

Now showing items 321-340 of 564

Universal Recommendations for the Management of Acute Diarrhea in Nonmalnourished Children.

Guarino A, Lo Vecchio A, Dias JA, Berkley JA, Boey C, Bruzzese D, Cohen MB, Cruchet S, Liguoro I, Salazar-Lindo E, Sandhu B, Sherman PM, Shimizu T. (Journal of pediatric gastroenterology and nutrition., 2018-11)

Objective: Despite a substantial consistency in recommendations for the management of children with acute gastroenteritis (AGE), a high variability in clinical practice and a high rate of inappropriate medical interventions ...
Guidelines for the treatment of dysentery (shigellosis): a systematic review of the evidence.

Williams PCM, Berkley JA. (Paediatrics and international child health., 2018-11)

Background: Shigella remains the primary cause of diarrhoea in paediatric patients worldwide and accounts for up to 40,000 deaths per year. Current guidelines for the treatment of shigellosis are based on data which are ...
Rapid intravenous rehydration of children with acute gastroenteritis and dehydration: a systematic review and meta-analysis.

Iro MA, Sell T, Brown N, Maitland K. (BMC pediatrics., 2018-02)

Background: The World Health Organization (WHO) recommends rapid intravenous rehydration, using fluid volumes of 70-100mls/kg over 3-6 h, with some of the initial volume given rapidly as initial fluid boluses to treat ...
Sickle Cell Anemia and Its Phenotypes.

Williams, TN; Thein, SL (Annual review of genomics and human genetics., 2018-08)

In the 100 years since sickle cell anemia (SCA) was first described in the medical literature, studies of its molecular and pathophysiological basis have been at the vanguard of scientific discovery. By contrast, the ...
Evaluation of Psychometric Properties and Factorial Structure of ADHD Module of K-SADS-PL in Children from Rural Kenya.

Kariuki SM, Newton CRJC, Abubakar A, Bitta MA, Odhiambo R, Phillips Owen J. (Journal of attention disorders., 2020-12)

Objective: We determined the reliability of The Kiddie-Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime (K-SADS-PL) for screening and diagnosing ADHD in children. Method: ...
Prevalence, intensity and associated risk factors of soil-transmitted helminth and schistosome infections in Kenya: Impact assessment after five rounds of mass drug administration in Kenya.

Okoyo C, Campbell SJ, Williams K, Simiyu E, Owaga C, Mwandawiro C. (PLoS neglected tropical diseases., 2020-10)

Background: In Kenya, over five million school age children (SAC) are estimated to be at risk of parasitic worms causing soil-transmitted helminthiasis (STH) and schistosomiasis. As such, the Government of Kenya launched ...
Community interventions in Low-And Middle-Income Countries to inform COVID-19 control implementation decisions in Kenya: A rapid systematic review.

Abdullahi L, Onyango JJ, Mukiira C, Wamicwe J, Githiomi R, Kariuki D, Mugambi C, Wanjohi P, Githuka G, Nzioka C, Orwa J, Oronje R, Kariuki J, Mayieka L. (PLOS One, 2020-12)

Globally, public health measures like face masks, hand hygiene and maintaining social distancing have been implemented to delay and reduce local transmission of COVID-19. To date there is emerging evidence to provide ...
Risk factors for loss to follow-up among at-risk HIV negative men who have sex with men participating in a research cohort with access to pre-exposure prophylaxis in coastal Kenya.

Wahome EW, Graham SM, Thiong'o AN, Mohamed K, Oduor T, Gichuru E, Mwambi J, van der Elst EM, Sanders EJ. (Journal of the International AIDS Society., 2020-10)

Introduction: Retention in preventive care among at-risk men who have sex with men (MSM) is critical for successful prevention of HIV acquisition in Africa. We assessed loss to follow-up (LTFU) rates and factors associated ...
Evaluation of morbidity in Schistosoma mansoni-positive primary and secondary school children after four years of mass drug administration of praziquantel in western Kenya.

Abudho BO, Guyah B, Ondigo BN, Ndombi EM, Ireri E, Carter JM, Riner DK, Kittur N, Karanja DMS, Colley DG. (Infect Dis Poverty, 2020-06)

Background: World Health Organization guidelines recommend preventive chemotherapy with praziquantel to control morbidity due to schistosomiasis. The primary aim of this cross-sectional study was to determine if 4 years ...
Addressing barriers of community participation and access to mass drug administration for lymphatic filariasis elimination in Coastal Kenya using a participatory approach.

Njomo DW, Kibe LW, Kimani BW, Okoyo C, Omondi WP, Sultani HM. (PLoS neglected tropical diseases., 2020-09)

Since the prioritization of Lymphatic Filariasis (LF) elimination in 1997, progress has been made in reducing disease transmission and burden. Validation of elimination through Transmission Assessment Surveys (TAS) in ...
Implementation challenges and opportunities for improved mass treatment uptake for lymphatic filariasis elimination: Perceptions and experiences of community drug distributors of coastal Kenya.

Njomo DW, Kimani BW, Kibe LW, Okoyo C, Omondi WP, Sultani HM. (PLoS neglected tropical diseases., 2020-12)

Community drug distributors (CDDs) who are volunteers have the responsibility of awareness creation, household census, drug distribution and record-keeping and are thus key stakeholders in the campaign for Lymphatic ...
Clinical Information Network Author Group. Examining which clinicians provide admission hospital care in a high mortality setting and their adherence to guidelines: an observational study in 13 hospitals.

Ogero M, Akech S, Malla L, Agweyu A, Irimu G, English M (Archives of disease in childhood., 2020-07)

Background: We explored who actually provides most admission care in hospitals offering supervised experiential training to graduating clinicians in a high mortality setting where practices deviate from guideline ...
Improvement of Dietary Diversity and Attitude Toward Recommended Feeding through Novel Community Based Nutritional Education Program in Coastal Kenya-An Intervention Study.

Hitachi M, Wanjihia V, Nyandieka L, Francesca C, Wekesa N, Changoma J, Muniu E, Ndemwa P, Honda S, Hirayama K, Karama M, Kaneko S. (International journal of environmental research and public health., 2020-10)

Community-based nutritional intervention to improve the practice of dietary diversity and child nutrition by community health workers (CHWs) involving Nyumba Kumi as small neighborhood units (SNUs) in communities has not ...
Implications of gestational age at antenatal care attendance on the successful implementation of a maternal respiratory syncytial virus (RSV) vaccine program in coastal Kenya.

Nyiro JU, Bukusi E, Mwaengo D, Walumbe D, Nyaguara A, Nyawanda B, Otieno N, Berkley JA, Munywoki P, Nokes DJ. (BMC Public Health, 2020-11)

Background: Maternal immunisation to boost respiratory syncytial virus (RSV) specific antibodies in pregnant women is a strategy to enhance infant protection. The timing of maternal vaccination during pregnancy may be ...
Tracking health sector priority setting processes and outcomes for human resources for health, five-years after political devolution: a county-level case study in Kenya.

Munywoki J, Kagwanja N, Chuma J, Nzinga J, Barasa E, Tsofa B. (International journal of Equity Health, 2020-09)

Background: Health sector priority setting in Low and Middle-Income Countries (LMICs) entails balancing between a high demand and low supply of scarce resources. Human Resources for Health (HRH) consume the largest allocation ...
Evaluation of Adaptive Feedback in a Smartphone-Based Game on Health Care Providers' Learning Gain: Randomized Controlled Trial.

Tuti T, Winters N, Edgcombe H, Muinga N, Wanyama C, English M, Paton C. (Journal of medical Internet research., 2020-07)

Background: Although smartphone-based emergency care training is more affordable than traditional avenues of training, it is still in its infancy, remains poorly implemented, and its current implementation modes tend to ...
Prevalence and risk factors of Schistosoma mansoni infection among children under two years of age in Mbita, Western Kenya.

Sassa M, Chadeka EA, Cheruiyot NB, Tanaka M, Moriyasu T, Kaneko S, Njenga SM, Cox SE, Hamano S. (PLoS neglected tropical diseases., 2020-08)

Despite growing evidence that infants and very young children can be infected with schistosomes, the epidemiological features and risk factors are not well described in this age group. We aimed to assess the prevalence of ...
Effectiveness of Rotarix <sup>®</sup> vaccine in Africa in the first decade of progressive introduction, 2009-2019: systematic review and meta-analysis.

Murunga N, P Otieno G, Maia M, N Agoti C. (Wellcome Open Research, 2020-09)

Background: Randomized controlled trials of licensed oral rotavirus group A (RVA) vaccines, indicated lower efficacy in developing countries compared to developed countries. We investigated the pooled effectiveness of ...
Predictors of health workers' knowledge about artesunate-based severe malaria treatment recommendations in government and faith-based hospitals in Kenya.

Machini, B; Zurovac, D; Amboko, B; Malla, L; Snow, RW; Kipruto, H; Achia, TNO (Malaria Journal, 2020-07)

Background: Health workers' knowledge deficiencies about artesunate-based severe malaria treatment recommendations have been reported. However, predictors of the treatment knowledge have not been examined. In this paper, ...
Trends in health workers' compliance with outpatient malaria case-management guidelines across malaria epidemiological zones in Kenya, 2010-2016.

Amboko B, Stepniewska K, Macharia PM, Machini B, Bejon P, Snow RW, Zurovac D. (Malaria Journal, 2020-11)

Background: Health workers' compliance with outpatient malaria case-management guidelines has been improving, specifically regarding the universal testing of suspected cases and the use of artemisinin-based combination ...

Now showing items 321-340 of 564

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