KEMRI Journals & Articles: Recent submissions

Now showing items 301-320 of 552

Rift Valley fever: biology and epidemiology

Wright D, Kortekaas J, Bowden TA, Warimwe GM (Journal of General Virology, 2019-08)

Rift Valley fever (RVF) is a mosquito-borne viral zoonosis that was first discovered in Kenya in 1930 and is now endemic throughout multiple African countries and the Arabian Peninsula. RVF virus primarily infects domestic ...
Oral versus Intravenous Antibiotics for Bone and Joint Infection

Li HK, Rombach I, Zambellas R, Walker AS, McNally MA, Atkins BL, Lipsky BA, Hughes HC, Bose D, Kümin M, Scarborough C, Matthews PC, Brent AJ, Lomas J, Gundle R, Rogers M, Taylor A, Angus B, Byren I, Berendt AR, Warren S, Fitzgerald FE, Mack DJF, Hopkins S, Folb J, Reynolds HE, Moore E, Marshall J, Jenkins N,Moran CE, Woodhouse AF, Stafford S, Seaton RA, Vallance C, Hemsley CJ, Bisnauthsing K, Sandoe JAT, Aggarwal I, Ellis SC, Bunn DJ, Sutherland RK, Barlow G, Cooper C, Geue C, McMeekin N, Briggs AH, Sendi P, Khatamzas E,Wangrangsimakul T, Wong T HN, Barrett LK, Alvand A, Old CF, Bostock J, Paul J, Cooke G, Thwaites GE, Bejon P, Scarborough M; OVIVA Trial Collaborators (The New England Journal of Medicine, 2019-01)

Background The management of complex orthopedic infections usually includes a prolonged course of intravenous antibiotic agents. We investigated whether oral antibiotic therapy is noninferior to intravenous antibiotic ...
Antiplasmodial prenylated flavanonols from Tephrosia subtriflora.

Muiva-Mutisya LM, Atilaw Y, Heydenreich M, Koch A, Akala HM, Cheruiyot AC, Brown ML, Irungu B, Okalebo FA, Derese S, Mutai C, Yenesew A. (Natural Product Research, 2018-06)

The CH2Cl2/MeOH (1:1) extract of the aerial parts of Tephrosia subtriflora afforded a new flavanonol, named subtriflavanonol (1), along with the known flavanone spinoflavanone B, and the known flavanonols MS-II (2) and ...
Infant and child mortality in relation to malaria transmission in KEMRI/CDC HDSS, Western Kenya: validation of verbal autopsy.

Amek NO, Van Eijk A, Lindblade KA, Hamel M, Bayoh N, Gimnig J, Laserson KF, Slutsker L, Smith T, Vounatsou P. (Malaria Journal, 2018-01)

Background: Malaria transmission reduction is a goal of many malaria control programmes. Little is known of how much mortality can be reduced by specific reductions in transmission. Verbal autopsy (VA) is widely used for ...
How Eliminating Malaria May Also Prevent Iron Deficiency in African Children.

Muriuki JM, Atkinson SH. (Pharmaceuticals (Basel)., 2018-10)

Malaria and iron deficiency are common among children living in sub-Saharan Africa. Several studies have linked a child's iron status to their future risk of malaria infection; however, few have examined whether malaria ...
The impact of malnutrition on childhood infections.

Walson JL, Berkley JA. (Current opinion in infectious diseases., 2018-06)

Purpose of review: Almost half of all childhood deaths worldwide occur in children with malnutrition, predominantly in sub-Saharan Africa and South Asia. This review summarizes the mechanisms by which malnutrition and ...
Biosafety and biosecurity capacity building: insights from implementation of the NUITM-KEMRI biosafety training model.

Muriithi B, Bundi M, Galata A, Miringu G, Wandera E, Kathiiko C, Odoyo E, Kamemba M, Amukoye E, Huqa S, Shah M, Inoue S, Ichinose Y. (Tropical Med Health, 2018-08)

The NUITM-KEMRI biosafety training program was developed for capacity building of new biosafety level three (BSL-3) laboratory users. The training program comprehensively covers biosafety and biosecurity theory and practice. ...
Gendered health systems: evidence from low- and middle-income countries.

Morgan R, Ayiasi RM, Barman D, Buzuzi S, Ssemugabo C, Ezumah N, George AS, Hawkins K, Hao X, King R, Liu T, Molyneux S, Muraya KW, Musoke D, Nyamhanga T, Ros B, Tani K, Theobald S, Vong S, Waldman L. (Health Res Policy Syst., 2018-07)

Background: Gender is often neglected in health systems, yet health systems are not gender neutral. Within health systems research, gender analysis seeks to understand how gender power relations create inequities in access ...
Universal Recommendations for the Management of Acute Diarrhea in Nonmalnourished Children.

Guarino A, Lo Vecchio A, Dias JA, Berkley JA, Boey C, Bruzzese D, Cohen MB, Cruchet S, Liguoro I, Salazar-Lindo E, Sandhu B, Sherman PM, Shimizu T. (Journal of pediatric gastroenterology and nutrition., 2018-11)

Objective: Despite a substantial consistency in recommendations for the management of children with acute gastroenteritis (AGE), a high variability in clinical practice and a high rate of inappropriate medical interventions ...
Guidelines for the treatment of dysentery (shigellosis): a systematic review of the evidence.

Williams PCM, Berkley JA. (Paediatrics and international child health., 2018-11)

Background: Shigella remains the primary cause of diarrhoea in paediatric patients worldwide and accounts for up to 40,000 deaths per year. Current guidelines for the treatment of shigellosis are based on data which are ...
Rapid intravenous rehydration of children with acute gastroenteritis and dehydration: a systematic review and meta-analysis.

Iro MA, Sell T, Brown N, Maitland K. (BMC pediatrics., 2018-02)

Background: The World Health Organization (WHO) recommends rapid intravenous rehydration, using fluid volumes of 70-100mls/kg over 3-6 h, with some of the initial volume given rapidly as initial fluid boluses to treat ...
Sickle Cell Anemia and Its Phenotypes.

Williams, TN; Thein, SL (Annual review of genomics and human genetics., 2018-08)

In the 100 years since sickle cell anemia (SCA) was first described in the medical literature, studies of its molecular and pathophysiological basis have been at the vanguard of scientific discovery. By contrast, the ...
Evaluation of Psychometric Properties and Factorial Structure of ADHD Module of K-SADS-PL in Children from Rural Kenya.

Kariuki SM, Newton CRJC, Abubakar A, Bitta MA, Odhiambo R, Phillips Owen J. (Journal of attention disorders., 2020-12)

Objective: We determined the reliability of The Kiddie-Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime (K-SADS-PL) for screening and diagnosing ADHD in children. Method: ...
Prevalence, intensity and associated risk factors of soil-transmitted helminth and schistosome infections in Kenya: Impact assessment after five rounds of mass drug administration in Kenya.

Okoyo C, Campbell SJ, Williams K, Simiyu E, Owaga C, Mwandawiro C. (PLoS neglected tropical diseases., 2020-10)

Background: In Kenya, over five million school age children (SAC) are estimated to be at risk of parasitic worms causing soil-transmitted helminthiasis (STH) and schistosomiasis. As such, the Government of Kenya launched ...
Community interventions in Low-And Middle-Income Countries to inform COVID-19 control implementation decisions in Kenya: A rapid systematic review.

Abdullahi L, Onyango JJ, Mukiira C, Wamicwe J, Githiomi R, Kariuki D, Mugambi C, Wanjohi P, Githuka G, Nzioka C, Orwa J, Oronje R, Kariuki J, Mayieka L. (PLOS One, 2020-12)

Globally, public health measures like face masks, hand hygiene and maintaining social distancing have been implemented to delay and reduce local transmission of COVID-19. To date there is emerging evidence to provide ...
Risk factors for loss to follow-up among at-risk HIV negative men who have sex with men participating in a research cohort with access to pre-exposure prophylaxis in coastal Kenya.

Wahome EW, Graham SM, Thiong'o AN, Mohamed K, Oduor T, Gichuru E, Mwambi J, van der Elst EM, Sanders EJ. (Journal of the International AIDS Society., 2020-10)

Introduction: Retention in preventive care among at-risk men who have sex with men (MSM) is critical for successful prevention of HIV acquisition in Africa. We assessed loss to follow-up (LTFU) rates and factors associated ...
Evaluation of morbidity in Schistosoma mansoni-positive primary and secondary school children after four years of mass drug administration of praziquantel in western Kenya.

Abudho BO, Guyah B, Ondigo BN, Ndombi EM, Ireri E, Carter JM, Riner DK, Kittur N, Karanja DMS, Colley DG. (Infect Dis Poverty, 2020-06)

Background: World Health Organization guidelines recommend preventive chemotherapy with praziquantel to control morbidity due to schistosomiasis. The primary aim of this cross-sectional study was to determine if 4 years ...
Addressing barriers of community participation and access to mass drug administration for lymphatic filariasis elimination in Coastal Kenya using a participatory approach.

Njomo DW, Kibe LW, Kimani BW, Okoyo C, Omondi WP, Sultani HM. (PLoS neglected tropical diseases., 2020-09)

Since the prioritization of Lymphatic Filariasis (LF) elimination in 1997, progress has been made in reducing disease transmission and burden. Validation of elimination through Transmission Assessment Surveys (TAS) in ...
Implementation challenges and opportunities for improved mass treatment uptake for lymphatic filariasis elimination: Perceptions and experiences of community drug distributors of coastal Kenya.

Njomo DW, Kimani BW, Kibe LW, Okoyo C, Omondi WP, Sultani HM. (PLoS neglected tropical diseases., 2020-12)

Community drug distributors (CDDs) who are volunteers have the responsibility of awareness creation, household census, drug distribution and record-keeping and are thus key stakeholders in the campaign for Lymphatic ...
Clinical Information Network Author Group. Examining which clinicians provide admission hospital care in a high mortality setting and their adherence to guidelines: an observational study in 13 hospitals.

Ogero M, Akech S, Malla L, Agweyu A, Irimu G, English M (Archives of disease in childhood., 2020-07)

Background: We explored who actually provides most admission care in hospitals offering supervised experiential training to graduating clinicians in a high mortality setting where practices deviate from guideline ...

Now showing items 301-320 of 552

Search DSpace

Advanced Search

Browse

All of DSpace
This Community
- By Issue Date
- Authors
- Titles
- Subjects

Recently added

KEMRI Journals & Articles: Recent submissions

Search DSpace

Browse

All of DSpace

This Community

My Account