Recently added

KEMRI Journals & Articles: Recent submissions

  • Rethinking health sector procurement as developmental linkages in East Africa. 
    Mackintosh M, Tibandebage P, Karimi Njeru M, Kariuki Kungu J, Israel C, Mujinja PGM (Social Science & Medicine, 2018-03)
    Health care forms a large economic sector in all countries, and procurement of medicines and other essential commodities necessarily creates economic linkages between a country's health sector and local and international ...
  • Pregnancy outcomes among HIV-infected women who conceived on antiretroviral therapy. 
    Stringer EM, Kendall MA, Lockman S, Campbell TB, Nielsen-Saines K, Sawe F, CuUvin S, Wu X, Currier JS. (PLOS One, 2018-07)
    As antiretroviral therapy (ART) expands in resource-limited settings, understanding the impact of ART on pregnancy outcomes is critical. We analyzed women who became pregnant on ART while enrolled in a clinical trial ...
  • Deciphering the targets of retroviral protease inhibitors in Plasmodium berghei. 
    Onchieku NM, Mogire R, Ndung'u L, Mwitari P, Kimani F, Matoke-Muhia D, Kiboi D, Magoma G. (PLOS One, 2018-08)
    Retroviral protease inhibitors (RPIs) such as lopinavir (LP) and saquinavir (SQ) are active against Plasmodium parasites. However, the exact molecular target(s) for these RPIs in the Plasmodium parasites remains poorly ...
  • Emotional and Behavioral Problems in Children and Adolescents in Central Kenya. 
    Magai DN, Malik JA, Koot HM. (Child Psychiatry Hum Dev., 2018-08)
    Emotional and behavioral problems (EBP) during childhood and adolescence are a common concern for parents and mental health stakeholders. However, little has been documented about their prevalence in Kenyan children and ...
  • Dosing of Ceftriaxone and Metronidazole for Children With Severe Acute Malnutrition. 
    Standing JF, Ongas MO, Ogwang C, Kagwanja N, Murunga S, Mwaringa S, Ali R, Mturi N, Timbwa M, Manyasi C, Mwalekwa L, Bandika VL, Ogutu B, Waichungo J, Kipper K, Berkley JA (Clin Pharmacol Ther., 2018-12)
    Infants and young children with severe acute malnutrition (SAM) are treated with empiric broad-spectrum antimicrobials. Parenteral ceftriaxone is currently a second-line agent for invasive infection. Oral metronidazole ...
  • The clinical epidemiology of sickle cell anemia In Africa. 
    Macharia AW, Mochamah G, Uyoga S, Ndila CM, Nyutu G, Makale J, Tendwa M, Nyatichi E, Ojal J, Shebe M, Awuondo KO, Mturi N, Peshu N, Tsofa B, Scott JAG, Maitland K, Williams TN. (American Journal of Hematology, 2018-03)
    Sickle cell anemia (SCA) is the commonest severe monogenic disorders of humans. The disease has been highly characterized in high-income countries but not in sub-Saharan Africa where SCA is most prevalent. We conducted ...
  • Problem Gambling among Young People in Sub-Saharan Africa. 
    Ssewanyana D, Bitanihirwe B. (Front Public Health., 2018-02)
    Gambling is a cross-cultural and global activity which typically involves the wagering of money or an item of monetary value on an outcome that is governed by chance. Although gambling is positioned as a legitimate ...
  • Nasopharyngeal Pneumococcal Carriage in Nigeria: a two-site, population-based survey. 
    Adetifa IMO, Adamu AL, Karani A, Waithaka M, Odeyemi KA, Okoromah CAN, Bello MM, Abubakar IS, Inem V, Scott JAG. (Scientific Reports, 2018-02)
    Changes in nasopharyngeal (NP) carriage of vaccine-type (VT) Streptococcus pneumoniae can be used to assess the effectiveness of a pneumococcal conjugate vaccine (PCV10). We conducted a baseline carriage survey in rural ...
  • Antimicrobial resistance among children in subSaharan Africa. 
    Williams PCM, Isaacs D, Berkley JA. (Lancet Infectious Diseases, 2018-02)
    Antimicrobial resistance is an important threat to international health. Therapeutic guidelines for empirical treatment of common life-threatening infections depend on available information regarding microbial aetiology ...
  • Health Risk Behaviour among Adolescents Living with HIV in Sub-Saharan Africa: A Systematic Review and Meta-Analysis. 
    Ssewanyana D, Mwangala PN, van Baar A, Newton CR, Abubakar A. (BioMed Research International, 2018-01)
    The burden of health risk behaviour (HRB) among adolescents living with HIV (ALWHIV) in sub-Saharan Africa (SSA) is currently unknown. A systematic search for publications on HRB among ALWHIV in SSA was conducted in ...
  • What Is Resilience and How Can It Be Nurtured? A Systematic Review of Empirical Literature on Organizational Resilience. 
    Barasa E, Mbau R, Gilson L. (International Journal of Health Policy and Management, 2018-06)
    Background: Recent health system shocks such as the Ebola outbreak of 2014-2016 and the global financial crisis of 2008 have generated global health interest in the concept of resilience. The concept is however not new, ...
  • Suicide in a rural area of coastal Kenya. 
    Bitta MA, Bakolis I, Kariuki SM, Nyutu G, Mochama G, Thornicroft G, Newton CRJC. (BMC psychiatry, 2018-08)
    Background: Suicide accounts for approximately 1.4% of deaths globally and is the 15th leading cause of death overall. There are no reliable data on the epidemiology of completed suicide in rural areas of many developing ...
  • Expectations for nursing care in newborn units in Kenya: moving from implicit to explicit standards. 
    Murphy GAV, Omondi GB, Gathara D, Abuya N, Mwachiro J, Kuria R, TallamKimaiyo E, English M. (BMJ Global Health, 2018-03)
    Neonatal mortality currently accounts for 45% of all child mortality in Kenya, standing at 22 per 1000 live births. Access to basic but high quality inpatient neonatal services for small and sick newborns will be key in ...
  • What characteristics of provider payment mechanisms influence health care providers' behaviour? 
    Kazungu JS, Barasa EW, Obadha M, Chuma J. (International journal of health planning and management, 2018-10)
    Background Provider payment mechanisms (PPMs) create incentives or signals that influence the behaviour of health care providers. Understanding the characteristics of PPMs that influence health care providers' behaviour ...
  • The NeuroDev Study: Phenotypic and Genetic Characterization of Neurodevelopmental Disorders in Kenya and South Africa 
    de Menil V, Hoogenhout M, Kipkemoi P, Kamuya D, Eastman E, Galvin A, Mwangasha K, de Vries J, Kariuki SM, Murugasen S, Mwangi P, Singh I, Stein DJ, Abubakar A, Newton CR, Donald KA, Robinson E (Cell Press, 2019-01)
    he NeuroDev study will deeply phenotype cognition, behavior, dysmorphias, and neuromedical traits on an expected cohort of 5,600 Africans (1,800 child cases, 1,800 child controls, and 1,900 parents) and will collect whole ...
  • Mosquito microevolution drives Plasmodium falciparum dynamics 
    Gildenhard M, Rono EK, Diarra A, Boissière A, Bascunan P, Carrillo- Bustamante P, Camara D, Krüger H, Mariko M, Mariko R, Mireji P, Nsango SE, Pompon J, Reis Y, Rono MK, Seda PB, Thailayil J, Traorè A, Yapto CV, Awono- Ambene P, Dabiré RK, Diabaté A, Masiga D, Catteruccia F, Morlais I, Diallo M, Sangare D, Levashina EA (Nature, 2019-06)
    Malaria, a major cause of child mortality in Africa, is engendered by Plasmodium parasites that are transmitted by anopheline mosquitoes. Fitness of Plasmodium parasites is closely linked to the ecology and evolution of ...
  • Implementation of Good Clinical Laboratory Practice in an Immunology Basic Research Laboratory: The KEMRI-Wellcome Trust Research Laboratories Experience 
    Gumba H, Musyoki J, Mosobo M, Lowe B (American Journal of Clinical Pathology, 2019-02)
    Objectives: Good Clinical Laboratory Practice (GCLP) is a standard that ensures quality and reliability of research data by adopting the principles of Good Laboratory Practice and Good Clinical Practice. Even though ...
  • Corrigendum: Sepsis: Changing Definitions, Unchanging Treatment 
    Obonyo NG, Schlapbach LJ, Fraser JF (Frontiers, 2020-01)
    The recently revised Sepsis-3 definitions were based on criteria that were derived and validated in adult patient databases from high income countries. Both sepsis and septic shock continue to account for a substantial ...
  • Tackling the triple threats of childhood malnutrition 
    Mwangome M, Prentice AM (BMC Medicine, 2019-11)
    The term 'double burden of malnutrition' is usually interpreted in terms of the physical status of children: stunted and wasted children on the one hand and overweight/obese children on the other. There is a third category ...
  • Implementing a quality management system using good clinical laboratory practice guidelines at KEMRI-CMR to support medical research 
    Gumba H, Waichungo J, Lowe B, Mwanzu A, Musyimi R, Thitiri J, Tigoi C, Kamui M, Berkley JA, Ngetich R, Kavai S, Kariuki S (Wellcome Open Research, 2019-06)
    Background: Good Clinical Laboratory Practice (GCLP) is a standard that helps ensure the quality and reliability of research data through principles of Good Laboratory Practice (GLP) and Good Clinical Practice (GCP). The ...

Search DSpace


Advanced Search

Browse

My Account