Limited Added Value of Oropharyngeal Swabs for Detecting Pneumococcal Carriage in Adults.

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dc.contributor.author Farrar, JL
dc.contributor.author Odiembo, H
dc.contributor.author Odoyo, A
dc.contributor.author Bigogo, G
dc.contributor.author Kim, L
dc.contributor.author Lessa, FC
dc.contributor.author Feikin, DR
dc.contributor.author Breiman, RF
dc.contributor.author Whitney, CG
dc.contributor.author Carvalho, MG
dc.contributor.author Pimenta, FC
dc.date.accessioned 2024-07-18T08:47:59Z
dc.date.available 2024-07-18T08:47:59Z
dc.date.issued 2020-08
dc.identifier.uri https://doi.org/10.1093%2Fofid%2Fofaa368
dc.identifier.uri http://repository.kemri.go.ke:8080/xmlui/handle/123456789/719
dc.description.abstract We compared pneumococcal isolation rates and evaluated the benefit of using oropharyngeal (OP) specimens in addition to nasopharyngeal (NP) specimens collected from adults in rural Kenya. Of 846 adults, 52.1% were colonized; pneumococci were detected from both NP and OP specimens in 23.5%, NP only in 22.9%, and OP only in 5.7%. Ten-valent pneumococcal conjugate vaccine strains were detected from both NP and OP in 3.4%, NP only in 4.1%, and OP only in 0.7%. Inclusion of OP swabs increased carriage detection by 5.7%; however, the added cost of collecting and processing OP specimens may justify exclusion from future carriage studies among adults. en_US
dc.language.iso en en_US
dc.publisher Open forum infectious diseases. en_US
dc.subject adults, carriage, colonization, nasopharyngeal, oropharyngeal, Streptococcus pneumoniae en_US
dc.title Limited Added Value of Oropharyngeal Swabs for Detecting Pneumococcal Carriage in Adults. en_US
dc.type Article en_US


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