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KEMRI Journals & Articles: Recent submissions

  • Urban Ecology of Arboviral Mosquito Vectors Along the Kenyan Coast 
    Karisa, Jonathan; Muriu, Simon; Omuoyo, Donwilliams; Karia, Boniface; Ngari, Moses; Nyamwaya, Doris; Rono, Martin; Warimwe, George; Mwangangi, Joseph; Mbogo, Charles M. (Oxford Academic, 2021-01)
    The purpose of this study was to determine the ecology of the common arboviral mosquito vectors in Mombasa, Kilifi and Malindi urban areas of coastal Kenya. Mosquito larvae were collected using standard dippers and pipettes. ...
  • Malaria micro-stratification using routine surveillance data in Western Kenya 
    Alegana, Victor A.; Suiyanka, Laurissa; Macharia, Peter M.; Muchangi, Grace Ikahu; Snow, Robert W. (BMC, 2021-01)
    Background There is an increasing need for finer spatial resolution data on malaria risk to provide micro-stratification to guide sub-national strategic plans. Here, spatial-statistical techniques are used to exploit ...
  • First do no harm: practitioners' ability to 'diagnose' system weaknesses and improve safety is a critical initial step in improving care quality 
    English, Mike; Ogola, Muthoni; Aluvaala, Jalemba; Gicheha, Edith; Irimu, Grace; McKnight, Jacob; Vincent, Charles A. (BMJ Journals, 2021-04)
    Healthcare systems across the world and especially those in low-resource settings (LRS) are under pressure and one of the first priorities must be to prevent any harm done while trying to deliver care. Health care workers, ...
  • Detection and Characterization of Salmonella enterica Serotypes by Simple PCR Technologies 
    Kariuki, Samuel; Kiiru, John (Springer Link, 2020-09)
    Polymerase chain reaction (PCR) is a molecular-based technology that has revolutionized diagnostics and characterization of pathogens, and thus affecting how we understand disease landscape. This technology has been found ...
  • Tools for measuring medical internship experience: a scoping review 
    Zhao, Yingxi; Musitia, Peris; Boga, Mwanamvua; Gathara, David; Nicodemo, Catia; English, Mike (BMC, 2021-01)
    Background: Appropriate and well-resourced medical internship training is important to ensure psychological health and well-being of doctors in training and also to recruit and retain these doctors. However, most reviews ...
  • Clinical features to distinguish meningitis among young infants at a rural Kenyan hospital 
    Obiero, Christina W.; Mturi, Neema; Mwarumba, Salim; Ngari, Moses; Newton, Charles; Hensbroek, Michael Boele van; Berkley, James Alexander (BMJ Journals, 2021-02)
    Background: Detection of meningitis is essential to optimise the duration and choice of antimicrobial agents to limit mortality and sequelae. In low and middle-income countries most health facilities lack laboratory capacity ...
  • Designing paper-based records to improve the quality of nursing documentation in hospitals: A scoping review 
    Muinga, Naomi; Abejirinde, Ibukun-Oluwa Omolade; Paton, Chris; Mike, English; Zweekhorst, Marjolein (Wiley Online, 2021-01)
    Background: Inpatient nursing documentation facilitates multi-disciplinary team care and tracking of patient progress. In both high- and low- and middle-income settings, it is largely paper-based and may be used as a ...
  • Immune responses to malaria pre-erythrocytic stages: Implications for vaccine development 
    Abuga, Kelvin Mokaya; Jones-Warner, William; Hafalla, Julius Clemence R. (Wiley Online, 2021-02)
    Radiation-attenuated sporozoites induce sterilizing immunity and remain the 'gold standard' for malaria vaccine development. Despite practical challenges in translating these whole sporozoite vaccines to large-scale ...
  • Respiratory syncytial virus seasonality in three epidemiological zones of Kenya 
    Rose, Erica Billig; Nyawanda, Bryan O.; Munywoki, Patrick K.; Murunga, Nickson; Bigogo, Godfrey M.; Otieno, Nancy A.; Onyango, Clayton; Chaves, Sandra S.; Verani, Jennifer R.; Emukule, Gideon O.; Widdowson, Marc-Alain; Nokes, D. James; Gerber, Susan I.; Langley, Gayle E. (Wiley Online, 2021-03)
    Understanding respiratory syncytial virus (RSV) circulation patterns is necessary to guide the timing of limited-duration interventions such as vaccines. We describe RSV circulation over multiple seasons in three distinct ...
  • Antiplasmodial and antileishmanial flavonoids from Mundulea sericea 
    Chepkirui, Carolyne; Ochieng, Purity J.; Sarkar, Biswajyoti; Hussain, Aabid; Pal, Chiranjib; Yang, Li Jun; Coghi, Paolo; Akala, Hosea; Derese, Solomon; Ndakala, Albert; Heydenreich, Matthias; Wong, Vincent K. W.; Erdélyi, Máté; Yenesew, Abiy (Science Direct, 2021-03)
    Five known compounds (1-5) were isolated from the extract of Mundulea sericea leaves. Similar investigation of the roots of this plant afforded an additional three known compounds (6-8). The structures were elucidated using ...
  • Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Kenyan blood donors 
    Uyoga, Sophie; Adetifa, Ifedayo; Karanja, Henry; Nyagwange, James; Tuju, James; Wanjiku, Perpetual; Aman, Rashid; Tsofa, Benjamin; Mwangangi, Mercy; Amoth, Patrick; Kadondi, Kasera; Ng'ang'a, Wangari; Rombo, Charles; Yegon, Christine; Kithi, Khamisi; Odhiambo, Elizabeth; Rotich, Thomas; Orgut, Irene; Kihara, Sammy; Otiende, Mark; Bottomley, Christian; Mupe, Zonia; Kagucia, Eunice; Gallagher, Katherine; Etyang, Anthony; Voller, Shirine; Gitonga, John; Mugo, Daisy; Agoti, Charles; Otieno, Edward; Ndwiga, Leonard; Lambe, Teresa; Wright, Daniel; Barasa, Edwine; Bejon, Philip; Ochola-Oyier, Lynette; Agweyu, Ambrose; G Scott, Anthony; Warimwe, George (2021-01-01)
    The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa is poorly described. The first case of SARS-CoV-2 in Kenya was reported on 12 March 2020, and an overwhelming number of cases and deaths ...
  • High Incidence of Enteroaggregative Escherichia coli Among Food Handlers in Three Areas of Kenya: A Possible Transmission Route of Travelers’ Diarrhea 
    Joseph O. Oundo, MSc, PhD; Samuel M. Kariuki, PhD, Hamadi I. Boga, PhD, Faith W. Muli, PhD, Yoshio Iijima, PhD (2008)
    Background Contaminated food and water are acknowledged vehicles for the transmission of travelers’ diarrhea (TD). Importance of food handlers as reservoirs of enteroaggregative Escherichia coli (EAEC), enteropathogenic ...

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