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Now showing items 1554-1573 of 1809

Safety and anti-proliferative activity of Prunus africana, Warburgia stuhlmannii and Maytenus senegalensis extracts in breast and colon cancer cell lines

Nabende, Namukhosi Patricia (2015)

Cancer is the leading cause of death worldwide. In Kenya, different cancer cases have been witnessed all over the country. The emphasis of diseases like malaria, Human Immunodeficiency Virus (HIV) and tuberculosis has ...
Safety and Tolerability of Mass Diethylcarbamazine and Albendazole Administration for the Elimination of Lymphatic Filariasis in Kenya: An Active Surveillance Study

Khaemba, C; Barry, A; Omondi, WP; Bota, K; Matendechero, S; Wandera, C; Siyoi, F; Kirui, E; Oluka, M; Nambwa, P; Gurumurthy, P; Njenga, SM; Guantai, A; Aklillu, E (Pharmaceuticals (Basel), 2021-03)

Preventive chemotherapy with diethylcarbamazine citrate (DEC) and albendazole (ALB) is the core intervention strategy to eliminate lymphatic filariasis (LF). We conducted a large-scale prospective active safety surveillance ...
Safety, efficacy and acceptability of praziquantel in the treatment of Schistosoma haematobium in pre-school children of Kwale County, Kenya

BRIDGET WANJIKU KIMANI; Amos K. Mbugua, Jimmy H. Kihara, Murima Ng’ang’a, Doris W. Njomo (PLoS Neglected Tropical Diseases, 2018-10)

Background The recommended strategy for control of schistosomiasis is preventive chemotherapy with praziquantel (PZQ). Pre-school children (PSC) are excluded from population treatment programs. In high endemic areas, ...
Safety, efficacy and acceptability of praziquantel in the treatment of Schistosoma haematobium in pre-school children of Kwale County, Kenya.

Kimani BW, Mbugua AK, Kihara JH, Ng'ang'a M, Njomo DW. (PLoS neglected tropical diseases., 2018-10)

Background: The recommended strategy for control of schistosomiasis is preventive chemotherapy with praziquantel (PZQ). Pre-school children (PSC) are excluded from population treatment programs. In high endemic areas, ...
Scalable Workflows and Reproducible Data Analysis for Genomics

Strozzi F, Janssen R, Wurmus R, Crusoe MR, Githinji G, Di Tommaso P, Belhachemi D, Möller S, Smant G, de Ligt J, Prins P (Springer Link, 2019-07)

Biological, clinical, and pharmacological research now often involves analyses of genomes, transcriptomes, proteomes, and interactomes, within and between individuals and across species. Due to large volumes, the analysis ...
Schistosoma mansoni among pre-school children in Musozi village, Ukerewe Island, North-Western-Tanzania: prevalence and associated risk factors

DEODATUS M. RUGANUZA; Humphrey D. Mazigo, Rebecca Waihenya, Domenica Morona, and Gerald M. Mkoji (Parasit Vectors, 2015)

Background: Recent evidence indicates that pre-school children (PSC) living in S. mansoni highly endemic areas are at similar risk of schistosomiasis infection and morbidity as their school aged siblings. Recognizing this ...
. A scoping review of breastfeeding peer support models applied in hospital settings.

Chepkirui, D; Nzinga, J; Jemutai, J; Tsofa, B; Jones, C; Mwangome, M (International breastfeeding journal, 2020-11)

Background: The 2013 updated guidelines on management of severe acute malnutrition in infants and children recommends the support of exclusive breastfeeding. These guidelines are inconsistently applied in low and middle ...
SEARCH Human Immunodeficiency Virus (HIV) Streamlined Treatment Intervention Reduces Mortality at a Population Level in Men with Low CD4 Counts.

Kamya, MR; Petersen, ML; Kabami, J; Ayieko, J; Kwariisima, D; Sang, N; Clark, TD; Schwab, J; Charlebois, ED; Cohen, CR; Bukusi, EA; Peng, J; Jain, V; Chen, YH; Chamie, G; Balzer, LB; Havlir, DV (Clinical Infectious Diseases, 2021-03)

Background: We tested the hypothesis that patient-centered, streamlined human immunodeficiency virus (HIV) care would achieve lower mortality than the standard treatment model for persons with HIV and CD4 ≤ 350/uL in the ...
Self-medication in Pregnancy and Associated Factors among Antenatal Patients of a Tertiary Facility in North-Eastern Nigeria

Yahkub Babatunde Mutalub, Monsurat Abdulwahab, Saidu Abubakar Kadas, Saleh Ahmed, Rehinatu Adejumo, Zainab Gambo Ibrahim, Hashiya Mohammed Gungura (2022)

BACKGROUND Self-medication during pregnancy is common. Some drugs could cause severe adverse effects that are sometimes life-threatening and harm pregnant mothers and fetuses. We evaluated the prevalence of self-medication ...
Sensorineural Hearing Loss among Hypertensive Patients Attending Cardiac Institute in Tanzania: A cross-sectional study

Enica Richard Massawe, Benjamin Mongi, Perfect Kishevo, Pedro Pallangyo (2023)

INTRODUCTION Hypertension is among non-communicable diseases worldwide and it has been associated with sensorineural hearing loss. Almost 1.39 billion people (1 out of 4 adults) have hypertension and this figure is expected ...
Sero-epidemiology and molecular characterization of Rickettsiae infecting humans, selected animals and arthropod vectors in Asembo, western Kenya, 2007-201

Maina, Alice N. (2012)

Rickettsiae are gram negative obligate intracellular bacteria in the class α proteobacteria. They are transmitted by arthropod vectors, including fleas, ticks, mites, andbody lice. The prevalence of rickettsial infections ...
Sero-Epidemiology Of Selected Arboviruses Among Febrile Patients In The Lake/River Basins Of Lake Baringo, Lake Naivasha And River Tana, Kenya

Tigoi, Caroline Chepngeno (2015)

Arboviruses cause emerging and re-emerging infections affecting humans and animals. They are spread primarily by blood-sucking insects such as mosquitoes, ticks, midges and sand flies. Changes in climate, ecology, ...
Sero-Prevalence And Factors Associated With Brucellosis In Goats And Sheep And Assessment Of Pastoralists, Knowledge Attitude And Practices Towards Brucellosis In Garissa County

Obonyo, Mark Odhiambo (2018)

Brucellosis, a zoonosis of major public health importance, is endemic in livestock in Kenya. Unfortunately, reliable data on Brucellosis in Kenya is scarce and data on seroprevalence and risk factors associated with small ...
Sero-prevalence and Factors Associated with HIV and HBV Infection in Patients Attending Juba Teaching Hospital, Southern Sudan

Akol, Johnson Mayik (2010)

HIV/AIDS and Hepatitis B Virus (HBV) are among the major causes of morbidity and mortality worldwide, with HIV affecting approximately 40.3 million people worldwide. Sub-Sahara Africa bears the greatest burden for both ...
Sero-prevalence for Hepatitis B virus among pregnant women attending antenatal clinic in Juba Teaching Hospital, Republic of South Sudan

ANTHONY LAKU STEPHEN KIRBAK; Zipporah Ng’ang’a, Jared Omolo, Hakim Idris, Abdulmumini Usman, William Baguma Mbabazi (Pan Africa Medical Journal, 2017-02)

Introduction: hepatitis B virus infection is a major public health problem worldwide and in Africa. This would be the first ever documented study on epidemiology of Hepatitis B infections in the newly formed Republic of ...
Sero-prevalence of Coxiella burnetii infection in sheep and goats and associated factors in Baringo County, Kenya

Josphat Mulei Muema (2017)

Q fever is a highly endemic, globally distributed zoonosis caused by Coxiella burnetii. The pathogen host rage is varied although domestic small ruminants are the frequent source of human infection. The disease is ...
Sero-Prevalence of HIV -1 Subtypes and Risk Factors Associated with Infection among Truckers along Nairobi -Mombasa Highway, Kenya,

Mutua, Kyalo Mathew (2010)
Sero-prevalence of human cytomegalovirus infection and predisposing factors among HIV infected patients attending comprehensive care clinic at Kenyatta National Hospital, Kenya

RUTH WAMBUI GICHO; R. Waihenya, N. Ndegwa, M. Timothy, L. Muthami, M. Nzou, K. Mutai, R.W. Lihana (East African Medical Journal, 2017-03)

Background: Human Cytomegalovirus (hCMV) is one of the opportunistic infections in HIV patients. During an active infection it's a common cause of Pneumonia, retinitis, gastro-intestinal disease, and hepatitis. It is ...
Sero-Prevalence of Human Cytomegalovirus Infection and the Associated Factors among HIV Infected Patients Attending the Comprehensive Care clinic at the Kenyatta National Hospital, Kenya

Gicho, Ruth Wambui (2017)

Human Cytomegalovirus (hCMV) is a member of Herpes Virus family. During an active infection in HIV infected patients, it is one of the most common causes of pneumonia, retinitis, gastrointestinal disease, and hepatitis. ...
Sero-prevalence of spotted fever typhus and scrub typhus group rickettsioses among patients with acute febrile illiness in Kenya.

Thiga Jacqueline Wairimu (2015)

Rickettsiosis is a pathogenic bacterial infection which is rarely identified as a cause of illness in patients presenting with common symptoms such as fever and headache. In any case, rickettsiae are difficult to diagnose ...

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