Recently added

KEMRI Institutional Repository: Recent submissions

  • Effect of an Educational Intervention Program on Pregnant Women’s Ability to Cope with Childbirth Pain in Western Kenya 
    Mable Wanyonyi, Maximilla Wanzala, Mary Kipmerewo, Evans Raballah (2023)
    INTRODUCTION Childbirth pain has remained a major challenge to women of child-bearing age over the years. Studies have shown that most women are not aware of the coping strategies to employ during childbirth. Severe ...
  • Utilization of Cervical Cancer Screening Services among Women Aged 18 to 59 Years in Laikipia East Sub-County, Kenya 
    Lily N. Njoroge, Godfrey H. Mudhune, George Otieno, Grace Wanjau, Alison Yoos (2023)
    INTRODUCTION Cervical cancer, a preventable disease, continues to be the leading cause of death resulting from cancers in Kenya. Despite free cervical cancer screening services in all government hospitals in Laikipia ...
  • Prevalence and Determinants of Distress at the Start of Chemotherapy among Adult Cancer Patients in Two Tertiary Hospitals in Kenya 
    Francisca Mumbua Mwangangi., Drusilla Makworo, Joash Ronald Aluoch, Irene Mageto (2023)
    BACKGROUND Chemotherapy is considered the cornerstone in the treatment of many cancers, but it also comes with its challenges. The distress experienced by patients at the commencement of chemotherapy is a critical aspect ...
  • Patient Factors Associated with Complementary and Alternative Medicine Use Among Cancer Patients at a County Referral Hospital, Kenya 
    Bravin George Etole, Sherry Oluchina, Bernard Wambua Mbithi (2023)
    BACKGROUND Despite numerous global reports on the use of complementary and alternative medicine (CAM), no studies have been published regarding its use at Machakos Level 5 Hospital. Therefore, this study aims to identify ...
  • Factors Related to Sepsis in Critical Care Setting in Rwanda Selected Referral Hospital 
    Innocent Mwiseneza, Aurelia Nkomeje, Aline Umuhoza, Christian Mukwesi, Sylvestre Hategekimana (2023)
    BACKGROUND Sepsis is described as potentially fatal organ failure induced by an unbalanced host response to infection. Annual estimates put the number of sepsis cases at over 19 million. The number of sepsis-related deaths ...
  • Sensorineural Hearing Loss among Hypertensive Patients Attending Cardiac Institute in Tanzania: A cross-sectional study 
    Enica Richard Massawe, Benjamin Mongi, Perfect Kishevo, Pedro Pallangyo (2023)
    INTRODUCTION Hypertension is among non-communicable diseases worldwide and it has been associated with sensorineural hearing loss. Almost 1.39 billion people (1 out of 4 adults) have hypertension and this figure is expected ...
  • Virulence and Resistance Genes in Campylobacter Spp Isolated from Asymptomatic Children at Kibera Slum in Nairobi, Kenya 
    Gachau Mureithi, Dr. Celestine Makobe , Dr. Nduhiu Gitahi, Beatrice Wandia, Ben Brian, Dr. Eric Lelo (2023)
    BACKGROUND Campylobacter spp. are among the global causes of food poisoning and harbour virulence and resistance genes which play a role in invasion and antibiotic resistance. This study aimed to detect selected resistance ...
  • Prevalence of Wuchereria bancrofti and Plasmodium spp. Infection in Anopheles Mosquitoes and Human Blood Sampled from Selected Regions in Busia County, Western Kenya 
    Caroline Maina, Dr. Joe Bargul, Dr. Nancy Kenyatta, Dennis Getange, Dr. Luna Kamau (2023)
    INTRODUCTION Lymphatic filariasis and malaria are mosquito-borne diseases and are co-endemic in coastal Kenya. We evaluated the occurrence of co-infections with Wuchereria bancrofti and Plasmodium falciparum, the causative ...
  • Keeping people with epilepsy safe during the COVID-19 pandemic 
    French JA, Brodie MJ, Caraballo R, Devinsky O, Ding D, Jehi L, Jette N, Kanner A, Modi AC, Newton CR, Patel AA, Pennell PB, Perucca E, Sander JW, Scheffer IE, Singh G, Williams E, Wilmshurst J, Cross JH (Neurology Journals, 2020-06)
    Objectives To provide information on the effect of the coronavirus disease of 2019 (COVID-19) pandemic on people with epilepsy and provide consensus recommendations on how to provide the best possible care for people with ...
  • Disrupting gender norms in health systems: making the case for change 
    Hay K, McDougal L, Percival V, Henry S, Klugman J, Wurie H, Raven J, Shabalala F, Fielding-Miller R, Dey A, Dehingia N, Morgan R, Atmavilas Y, Saggurti N, Yore J, Blokhina E, Huque R, Barasa E, Bhan N, Kharel C, Silverman JG, Raj A; Gender Equality, Norms, and Health Steering Committee (The Lancet, 2019-06)
    Restrictive gender norms and gender inequalities are replicated and reinforced in health systems, contributing to gender inequalities in health. In this Series paper, we explore how to address all three through recognition ...
  • Rift Valley fever: biology and epidemiology 
    Wright D, Kortekaas J, Bowden TA, Warimwe GM (Journal of General Virology, 2019-08)
    Rift Valley fever (RVF) is a mosquito-borne viral zoonosis that was first discovered in Kenya in 1930 and is now endemic throughout multiple African countries and the Arabian Peninsula. RVF virus primarily infects domestic ...
  • Oral versus Intravenous Antibiotics for Bone and Joint Infection 
    Li HK, Rombach I, Zambellas R, Walker AS, McNally MA, Atkins BL, Lipsky BA, Hughes HC, Bose D, Kümin M, Scarborough C, Matthews PC, Brent AJ, Lomas J, Gundle R, Rogers M, Taylor A, Angus B, Byren I, Berendt AR, Warren S, Fitzgerald FE, Mack DJF, Hopkins S, Folb J, Reynolds HE, Moore E, Marshall J, Jenkins N,Moran CE, Woodhouse AF, Stafford S, Seaton RA, Vallance C, Hemsley CJ, Bisnauthsing K, Sandoe JAT, Aggarwal I, Ellis SC, Bunn DJ, Sutherland RK, Barlow G, Cooper C, Geue C, McMeekin N, Briggs AH, Sendi P, Khatamzas E,Wangrangsimakul T, Wong T HN, Barrett LK, Alvand A, Old CF, Bostock J, Paul J, Cooke G, Thwaites GE, Bejon P, Scarborough M; OVIVA Trial Collaborators (The New England Journal of Medicine, 2019-01)
    Background The management of complex orthopedic infections usually includes a prolonged course of intravenous antibiotic agents. We investigated whether oral antibiotic therapy is noninferior to intravenous antibiotic ...
  • Antiplasmodial prenylated flavanonols from Tephrosia subtriflora. 
    Muiva-Mutisya LM, Atilaw Y, Heydenreich M, Koch A, Akala HM, Cheruiyot AC, Brown ML, Irungu B, Okalebo FA, Derese S, Mutai C, Yenesew A. (Natural Product Research, 2018-06)
    The CH2Cl2/MeOH (1:1) extract of the aerial parts of Tephrosia subtriflora afforded a new flavanonol, named subtriflavanonol (1), along with the known flavanone spinoflavanone B, and the known flavanonols MS-II (2) and ...
  • Infant and child mortality in relation to malaria transmission in KEMRI/CDC HDSS, Western Kenya: validation of verbal autopsy. 
    Amek NO, Van Eijk A, Lindblade KA, Hamel M, Bayoh N, Gimnig J, Laserson KF, Slutsker L, Smith T, Vounatsou P. (Malaria Journal, 2018-01)
    Background: Malaria transmission reduction is a goal of many malaria control programmes. Little is known of how much mortality can be reduced by specific reductions in transmission. Verbal autopsy (VA) is widely used for ...
  • How Eliminating Malaria May Also Prevent Iron Deficiency in African Children. 
    Muriuki JM, Atkinson SH. (Pharmaceuticals (Basel)., 2018-10)
    Malaria and iron deficiency are common among children living in sub-Saharan Africa. Several studies have linked a child's iron status to their future risk of malaria infection; however, few have examined whether malaria ...
  • The impact of malnutrition on childhood infections. 
    Walson JL, Berkley JA. (Current opinion in infectious diseases., 2018-06)
    Purpose of review: Almost half of all childhood deaths worldwide occur in children with malnutrition, predominantly in sub-Saharan Africa and South Asia. This review summarizes the mechanisms by which malnutrition and ...
  • Biosafety and biosecurity capacity building: insights from implementation of the NUITM-KEMRI biosafety training model. 
    Muriithi B, Bundi M, Galata A, Miringu G, Wandera E, Kathiiko C, Odoyo E, Kamemba M, Amukoye E, Huqa S, Shah M, Inoue S, Ichinose Y. (Tropical Med Health, 2018-08)
    The NUITM-KEMRI biosafety training program was developed for capacity building of new biosafety level three (BSL-3) laboratory users. The training program comprehensively covers biosafety and biosecurity theory and practice. ...
  • Gendered health systems: evidence from low- and middle-income countries. 
    Morgan R, Ayiasi RM, Barman D, Buzuzi S, Ssemugabo C, Ezumah N, George AS, Hawkins K, Hao X, King R, Liu T, Molyneux S, Muraya KW, Musoke D, Nyamhanga T, Ros B, Tani K, Theobald S, Vong S, Waldman L. (Health Res Policy Syst., 2018-07)
    Background: Gender is often neglected in health systems, yet health systems are not gender neutral. Within health systems research, gender analysis seeks to understand how gender power relations create inequities in access ...
  • Universal Recommendations for the Management of Acute Diarrhea in Nonmalnourished Children. 
    Guarino A, Lo Vecchio A, Dias JA, Berkley JA, Boey C, Bruzzese D, Cohen MB, Cruchet S, Liguoro I, Salazar-Lindo E, Sandhu B, Sherman PM, Shimizu T. (Journal of pediatric gastroenterology and nutrition., 2018-11)
    Objective: Despite a substantial consistency in recommendations for the management of children with acute gastroenteritis (AGE), a high variability in clinical practice and a high rate of inappropriate medical interventions ...
  • Guidelines for the treatment of dysentery (shigellosis): a systematic review of the evidence. 
    Williams PCM, Berkley JA. (Paediatrics and international child health., 2018-11)
    Background: Shigella remains the primary cause of diarrhoea in paediatric patients worldwide and accounts for up to 40,000 deaths per year. Current guidelines for the treatment of shigellosis are based on data which are ...