Abstract:
INTRODUCTION
Measles  has  been  among  the  many  vaccine-preventable  diseases,  and  it  remains  a significant  public  health  concern  in  Kenya.  Immunization  coverage  is  the  most  common indicator  used  to  evaluate  the  performance  of  immunization  services.This  study  aimed  to assess the factors influencing measles-rubella second dose uptake among children aged 19-59 months in Mwingi Central sub-County. MATERIALS AND METHODS 
We used a descriptive cross-sectional study design and recruited 380 mothers using stratified proportionate sampling. We later selected children who received the first dose of the Measles-rubella vaccine in 2020 by simple random sampling. We used a semi-structured questionnaire for data collection. 
RESULTS
The measles-rubella uptake was 68.9% (262/380), whilethe different age groups of  the  mothers  had  the  following  uptake: 15-19  years,  20-24  years,  25-29  years,  30-34 years, 35-39 years and above 40 years were 60% (95% CI: 26.24% -87.84%), 63.8% (95% CI  48.52% -77.33%),  73.6%  (95%  CI:  65.16% -81.01%),  70.1%(95%  CI  60.93%-78.20%),  68.6%  (95%  CI  54.11%-80.89%)  and  53.8%  (95%  CI  33.37%-73.41%) respectively. Client-related determinants were significantly associated with the mother's residence,  employment  status,  religion,  knowledge  of  the  measles  vaccination  schedule and  on  the  uptake  of  the  second  dose  of  the  measles-rubella  vaccine  (P-value  <  0.05). Facility-related  determinants  showed  a  significant  association  between  distance  from households,  the  facility  always  being  open  and  the  uptake  of  the  second  dose  of  the measles-rubella vaccine for children between 19 -59 months (p-value < 0.05).
CONCLUSION 
The  measles-rubella  vaccine  uptake was  above  average  (68.9%),  and  uptake  of  the second  dose  was  significantly  associated  with  client-level  and  facility-related  factors.  The authors recommend that the Mwingi central sub-county health management team ensure the education  of  the  population  of  its  catchment  area  on  the  measles-rubella  second  dose vaccination schedule and that all immunizing health facilities are always open. Moreover, it should provision of outreach services for hard-to-reach communities.