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Now showing items 1-20 of 661

Accountability mechanisms and the value of relationships: experiences of front- line managers at subnational level in Kenya and South Africa.

Nxumalo N, Gilson L, Goudge J, Tsofa B, Cleary S, Barasa E, Molyneux S. (BMJ Global Health, 2018-07)

Resource constraints, value for money debates and concerns about provider behaviour have placed accountability 'front and centre stage' in health system improvement initiatives and policy prescriptions. There are a myriad ...
Accounting for clustering for self-reported outcomes in the design and analysis of population-based surveys: A case study of estimation of prevalence of epilepsy in Nairobi, Kenya.

Mwanga, D. M., Kipchirchir, I. C., Muhua, G. O., Newton, C. R., Kadengye, D. T. (Front Res Metr Anal, 2025-09)

Population-based surveys are common for estimation of important public health metrics such as prevalence. Often, survey data tend to have a hierarchical structure where households are clustered within villages or sites and ...
Adaptations to water stress and pastoralism in the Turkana of northwest Kenya

AJ Lea, IV Caldas, KM Garske, ER Gerlinger, JP Arroyo, J Echwa, M Gurven, C Handley, JC Kahumbu, J Kamau, P Kinyua, F Lotukoi, A Lopurudoi, S Lowasa, SN Njeru, R Mallarino, DJ Martins, PW Messer, C Miano, B Muhoya, J Peng, T Phung, JD Rabinowitz, A Roichman, R Siford, AC Stone, AM Taravella Oill, S Mathew, MA Wilson, JF Ayroles (2025-09)

The Turkana pastoralists of Kenya inhabit arid, water-limited environments and rely largely on livestock for subsistence. Working with Turkana communities, we sequenced 367 whole genomes and identified eight regions with ...
An adapted instrument to assess informed consent comprehension among youth and parents in rural western Kenya: a validation study

Afolabi MO, Rennie S, Hallfors DD, Kline T, Zeitz S, Odongo FS, Amek NO, Luseno WK. (BMJ Open, 2018-07)

Objective: To adapt and validate a questionnaire originally developed in a research setting for assessment of comprehension of consent information in a different cultural and linguistic research setting. Design: The ...
Addressing barriers of community participation and access to mass drug administration for lymphatic filariasis elimination in Coastal Kenya using a participatory approach.

Njomo DW, Kibe LW, Kimani BW, Okoyo C, Omondi WP, Sultani HM. (PLoS neglected tropical diseases., 2020-09)

Since the prioritization of Lymphatic Filariasis (LF) elimination in 1997, progress has been made in reducing disease transmission and burden. Validation of elimination through Transmission Assessment Surveys (TAS) in ...
Addressing power asymmetries in global health: Imperatives in the wake of the COVID-19 pandemic.

Abimbola, S; Asthana, S; Montenegro, C; Guinto, R R; Jumbam, DT; Louskieter, L; Kabubei, KM; Munshi, S; Muraya, K; Okumu, F; Saha, S; Saluja, D; Pai, M (PLOS Med, 2021-04)
Addressing the challenges of estimating the target population in calculation of routine infant immunization coverage in Kenya

Christine Karanja-Chege, Ambrose Agweyu , Fred Were , Michael Boele van Hensbroek , William Ogallo (PLOS GLOB PUBLIC HEALTH, 2025-07)

Target population estimation for immunization coverage calculations from census data is often inaccurate. This study aimed to evaluate the accuracy of the traditional census extrapolation method in comparison with three ...
Adherence to Covid-19 Prevention Protocols among Adults Residing in Kitui Central Sub-County, Kitui County, Kenya

Faith Ngui, Gichure Josphat, Ndwiga Taratisio, Francis Matheka Muoki (2023)

INTRODUCTION The COVID-19 pandemic wreaked worldwide havoc resulting in at least 6.9 million deaths. In Kenya, the government laid out behavioural and social mitigation strategies to control its spread. This study aimed ...
Adolescent perceptions about participating in HIV-related research studies.

Simons-Rudolph, AP; Iritani, BJ; Odongo, FS; Rennie, S; Gilbertson, A; Kwaro, D; Luseno, WK (Oxford : Elsevier Ltd, 2020-09)

The rising incidence of infection among youth in sub-Saharan Africa makes HIV-related research among younger people a top priority. There remains, however, a lack of consistent and unambiguous ethical principles and guidance ...
Adoption of routine virologic testing and predictors of virologic failure among HIV-infected children on antiretroviral treatment in western Kenya.

Kadima J, Patterson E, Mburu M, Blat C, Nyanduko M, Bukusi EA, Cohen C, Oyaro P, Abuogi L. (PLOS One, 2018-11)

Background: Access to routine virologic monitoring, critical to ensuring treatment success, remains limited in low- and middle-income countries. We report on implementation of routine viral load (VL) monitoring and risk ...
Aflatoxin exposure and mortality in acutely ill children: results from the CHAIN network cohort

Xia, L., Wu, H., Saleem, A. F., Mupere, E., Lancioni, C., Diallo, H., Potani, I., Ali, S. A., Voskuijl, W., Chisti, M. J., Shahid, A. S. M. S. B., Timbwa, M., Mwaringa, S., Tigoi, C., Ngari, M., Singa, B., Tickell, K. D., Njunge, J., Bandsma, R., Ahmed, T., Berkley, J., Walson, J. L., Gong, Y., Routledge, M. N. (BMJ Glob Health, 2025-07)

Background Chronic exposure to aflatoxins is associated with liver cancer, impaired child growth, and compromised immune function. The Childhood Acute Illness and Nutrition (CHAIN) Network cohort was established to identify ...
Age differences in immunity to human seasonal coronaviruses and the immunogenicity of ChAdOx1 nCoV-19 (AZD1222)

Sandra Belij-Rammerstorfer , Emma Sheehan , Grace Li , Sagida Bibi , Daniel Wright, Merryn Voysey , Cameron Bissett , Ninisha Barman , Susana Camara , Audrey Au Yong , Sue Ann Costa Clemens , Mae Harris , Amy Flaxman , Jordan Barrett , Khiyam Hussain , Gareth Lipunga , Robert H Shaw , Holly Smith , Stanley Cheruiyot , John N Gitonga , Daisy Mugo , Henry K Karanja , George M Warimwe , Mainga M Hamaluba , Lily Y Weckx , Andrew J Pollard , Teresa Lambe (PUblmed, 2025-08)

Background: ChAdOx1 nCoV-19 (AZD1222) vaccine was widely deployed to protect against severe COVID-19 in adults, but the relationship between pre-existing immunity to human seasonal coronaviruses (HCoVs) and vaccine-induced ...
Air pollution and health in Rwandan and Kenyan schools cooking with polluting fuels: a cross sectional impact study

Willah Nabukwangwa, R ́ev ́erien Rutayisire, Esther A. Kalkman-Boudewijns, Federico Lorenzetti, Emily Nix, Bernard Mutariyani, Gohole Arthur-Akaranga, Betty Koech, Joan Kinya, Matthew Shupler, Ghislaine Rosa, Elisa Puzzolo, Claude Mambo Muvunyi, Theoneste Ntakirutimana, Daniel Pope, Clarisse Musanabaganwa, James Mwitari, Vasileios N. Matthaios (ENVIRONMENTAL RESEARCH, 2025-08)

School meals across Sub-Saharan Africa are typically prepared using biomass on inefficient stoves, resulting in high air pollution levels that might affect learners and staff. However, there is a paucity of air pollution ...
Airway response to respiratory syncytial virus has incidental antibacterial effects

Sande CJ, Njunge JM, Mwongeli Ngoi J, Mutunga MN, Chege T, Gicheru ET, Gardiner EM, Gwela A, Green CA, Drysdale SB, Berkley JA, Nokes DJ, Pollard AJ (Nature, 2019-05)

RSV infection is typically associated with secondary bacterial infection. We hypothesise that the local airway immune response to RSV has incidental antibacterial effects. Using coordinated proteomics and metagenomics ...
Always leave the audience wanting more: An entertaining approach to stimulate engagement with health research among publics in coastal Kenya through 'Magnet Theatre'.

Sanga, G; Jao, I; Mumba, N; Mwalukore, S; Kamuya, D; Davies, A (Wellcome Open Research, 2021-01)

Background: Magnet Theatre (MT), a form of participatory community theatre, is one of several public engagement approaches used to facilitate engagement between KEMRI-Wellcome Trust Research Programme (KWTRP) researchers ...
Anthropometric measures and their association with risk factors for cardio-metabolic diseases in Kenyan adults.

Lajeunesse-Trempe F, Dufour R, du Souich P, Paquette M, Kaduka LU, Christensen DL. (Annals of Human Biology, 2019-01)

Background: The prevalence of cardio-metabolic diseases (CMD) is drastically increasing worldwide. Anthropometric measures of fat accumulation are correlated with CMD and Metabolic Syndrome (MS), but few studies have ...
Anti-proliferative activity of Grewia villosa ethyl acetate extract on cervical cancer HeLa cell line: Mechanistic insights through network Pharmacology and functional assays approach.

Sally Wambui Kamau, Mercy Jepkorir , Gilbert Kipkoech , Inyani John Lino Lagu , Wesley Kanda , Susan Kibunja , Rakita Letoluo , Shadrack Barmasai , Alice Wanyoko , Vincent Ruttoh , James Kuria , Peter Githaiga Mwitari , Mathew Piero Ngugi , Sospeter Ngoci Njeru (Public Library of Science (PLoS), 2025-09)

Grewia villosa is a plant native to Kenya, with a traditional history among Ambeere people for treating and managing prostate and breast cancers. Previous scientific studies have demonstrated its anti-inflammatory and ...
Antibiotic use in Kenyan public hospitals: Prevalence, appropriateness and link to guideline availability

Maina, M; Mwaniki, P; Odira, E; Kiko, N; McKnight, J; Schultsz, C; English, M (International journal of infectious diseases, 2020-10)

Objective: To examine prescription patterns and explore to what extent guidelines are available and how they might influence treatment appropriateness among hospitalised patients in Kenyan hospitals. Methods: Data on ...
Antibiotics and activity spaces: protocol of an exploratory study of behaviour, marginalisation and knowledge diffusion.

Haenssgen MJ, Charoenboon N, Zanello G, Mayxay M, Reed-Tsochas F, Jones COH,Kosaikanont R, Praphattong P, Manohan P, Lubell Y, Newton PN, Keomany S, Wertheim HFL, Lienert J, Xayavong T, Warapikuptanun P, Khine Zaw Y, U-Thong P,Benjaroon P, Sangkham N, Wibunjak K, Chai-In P, Chailert S, Thavethanutthanawin P, Promsutt K, Thepkhamkong A, Sithongdeng N, Keovilayvanh M, Khamsoukthavong N, Phanthasomchit P, Phanthavong C, Boualaiseng S, Vongsavang S, Greer RC, Althaus T, Nedsuwan S, Intralawan D, Wangrangsimakul T, Limmathurotsakul D, Ariana P. (BMJ Global Health, 2018-03)

Background: Antimicrobial resistance (AMR) is a global health priority. Leading UK and global strategy papers to fight AMR recognise its social and behavioural dimensions, but current policy responses to improve the ...
Antibody Responses to Crude Gametocyte Extract Predict <i>Plasmodium falciparum</i> Gametocyte Carriage in Kenya

Omondi, BR; Muthui, MK; Muasya, WI; Orindi, B; Mwakubambanya, RS; Bousema, T; Drakeley, C; Marsh, K; Bejon, P; Kapulu, MC (Front Immunol, 2021-01)

Background: Malaria caused by Plasmodium falciparum remains a serious global public health challenge especially in Africa. Interventions that aim to reduce malaria transmission by targeting the gametocyte reservoir are key ...

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