Browsing KEMRI Research Papers by Title

Browsing KEMRI Research Papers by Title

Sort by: Order: Results:

  • Examining unit costs for COVID-19 case management in Kenya 
    Barasa, Edwine; Kairu, Angela; Ng'ang'a, Wangari; Maritim, Marybeth; Were, Vincent; Akech, Samuel; Mwangangi, Mercy (BMJ Journals, 2021-04)
    Introduction: We estimated unit costs for COVID-19 case management for patients with asymptomatic, mild-to-moderate, severe and critical COVID-19 disease in Kenya. Methods: We estimated per-day unit costs of COVID-19 ...
  • First do no harm: practitioners' ability to 'diagnose' system weaknesses and improve safety is a critical initial step in improving care quality 
    English, Mike; Ogola, Muthoni; Aluvaala, Jalemba; Gicheha, Edith; Irimu, Grace; McKnight, Jacob; Vincent, Charles A. (BMJ Journals, 2021-04)
    Healthcare systems across the world and especially those in low-resource settings (LRS) are under pressure and one of the first priorities must be to prevent any harm done while trying to deliver care. Health care workers, ...
  • Health system responsiveness: a systematic evidence mapping review of the global literature 
    Khan, Gadija; Kagwanja, Nancy; Whyle, Eleanor; Gilson, Lucy; Molyneux, Sassy; Schaay, Nikki; Tsofa, Benjamin; Barasa, Edwine; Olivier, Jill (BMC, 2021-05)
    Background The World Health Organisation framed responsiveness, fair financing and equity as intrinsic goals of health systems. However, of the three, responsiveness received significantly less attention. Responsiveness ...
  • High Incidence of Enteroaggregative Escherichia coli Among Food Handlers in Three Areas of Kenya: A Possible Transmission Route of Travelers’ Diarrhea 
    Joseph O. Oundo, MSc, PhD; Samuel M. Kariuki, PhD, Hamadi I. Boga, PhD, Faith W. Muli, PhD, Yoshio Iijima, PhD (2008)
    Background Contaminated food and water are acknowledged vehicles for the transmission of travelers’ diarrhea (TD). Importance of food handlers as reservoirs of enteroaggregative Escherichia coli (EAEC), enteropathogenic ...
  • How urban 'informality' can inform response to COVID-19: a research agenda for the future 
    Onditi, Francis; Nyadera, Israel Nyaburi; Obimbo, Moses Madadi; Muchina, Samson Kinyanjui (Springer Link, 2021-01)
    In the era of increasingly defined ontological insecurity and uncertainty driven by the ravages of COVID-19, urban informal settlement has emerged as a source of resilience. Indeed, the effects of a pandemic transcends its ...
  • "I wish to remain HIV negative": Pre-exposure prophylaxis adherence and persistence in transgender women and men who have sex with men in coastal Kenya 
    Kimani, Makobu; van der Elst, Elise M.; Chirro, Oscar; Wahome, Elizabeth; Ibrahim, Fauz; Mukuria, Nana; Rinke de Wit, Tobias F.; Graham, Susan M.; Operario, Don; Sanders, Eduard J. (PLOS One Journals, 2021-01)
    Background: Transgender women (TGW) and men who have sex with men (MSM) in sub-Saharan Africa have high HIV acquisition risks and can benefit from daily pre-exposure prophylaxis (PrEP). We assessed PrEP adherence by measuring ...
  • Immune responses to malaria pre-erythrocytic stages: Implications for vaccine development 
    Abuga, Kelvin Mokaya; Jones-Warner, William; Hafalla, Julius Clemence R. (Wiley Online, 2021-02)
    Radiation-attenuated sporozoites induce sterilizing immunity and remain the 'gold standard' for malaria vaccine development. Despite practical challenges in translating these whole sporozoite vaccines to large-scale ...
  • The importance of supplementary immunisation activities to prevent measles outbreaks during the COVID-19 pandemic in Kenya 
    Mburu, C.N.; Ojal, J.; Chebet, R.; Akech, D.; Karia, B.; Tuju, J.; Sigilai, A.; Abbas, K.; Jit, M.; Funk, S.; Smits, G.; van Gageldonk, P.G.M.; van der Klis, F. R. M.; Tabu, C.; Nokes, D.J.; LSHTM CMMID COVID-19 Working Group; Scott, Jag; Flasche, S.; Adetifa, Imo (BMC, 2021-02)
    Background: The COVID-19 pandemic has disrupted routine measles immunisation and supplementary immunisation activities (SIAs) in most countries including Kenya. We assessed the risk of measles outbreaks during the pandemic ...
  • Integrating epidemiological and genetic data with different sampling intensities into a dynamic model of respiratory syncytial virus transmission 
    Kombe, Ivy K.; Agoti, Charles N.; Munywoki, Patrick K.; Baguelin, Marc; Nokes, D. James; Medley, Graham F. (PubMed, 2021-01)
    espiratory syncytial virus (RSV) is responsible for a significant burden of severe acute lower respiratory tract illness in children under 5 years old; particularly infants. Prior to rolling out any vaccination program, ...
  • Interpersonal psychotherapy delivered by nonspecialists for depression and posttraumatic stress disorder among Kenyan HIV-positive women affected by gender-based violence: Randomized controlled trial 
    Meffert, Susan M.; Neylan, Thomas C.; McCulloch, Charles E.; Blum, Kelly; Cohen, Craig R.; Bukusi, Elizabeth A.; Verdeli, Helen; Markowitz, John C.; Kahn, James G.; Bukusi, David; Thirumurthy, Harsha; Rota, Grace; Rota, Ray; Oketch, Grace; Opiyo, Elizabeth; Ongeri, Linnet (PLOS One Journals, 2021-01)
    Background: HIV-positive women suffer a high burden of mental disorders due in part to gender-based violence (GBV). Comorbid depression and posttraumatic stress disorder (PTSD) are typical psychiatric consequences of GBV. ...
  • Longitudinal-Survival Models for Case-Based Tuberculosis Progression 
    Kiplimo, Richard; Kosgei, Mathew; Mwangi, Ann; Onyango, Elizabeth; Ogero, Morris; Koske, Joseph (Frontiers, 2021-04)
    Introduction: Tuberculosis (TB) disease continues to be responsible for a high global burden with an estimated 10 million people falling ill each year and an estimated 1.45 million deaths. Widely carried out analyses to ...
  • Malaria micro-stratification using routine surveillance data in Western Kenya 
    Alegana, Victor A.; Suiyanka, Laurissa; Macharia, Peter M.; Muchangi, Grace Ikahu; Snow, Robert W. (BMC, 2021-01)
    Background There is an increasing need for finer spatial resolution data on malaria risk to provide micro-stratification to guide sub-national strategic plans. Here, spatial-statistical techniques are used to exploit ...
  • Molecular detection of Leishmania donovani, Leishmania major, and Trypanosoma species in Sergentomyia squamipleuris sand flies from a visceral leishmaniasis focus in Merti sub-County, eastern Kenya 
    Owino, Barrack O.; Mwangi, Jackline Milkah; Kiplagat, Steve; Mwangi, Hannah Njiriku; Ingonga, Johnstone M.; Chebet, Alphine; Ngumbi, Philip M.; Villinger, Jandouwe; Masiga, Daniel K.; Matoke-Muhia, Damaris (BMC, 2021-01)
    Background Visceral leishmaniasis (VL) and zoonotic cutaneous leishmaniasis (ZCL) are of public health concern in Merti sub-County, Kenya, but epidemiological data on transmission, vector abundance, distribution, and ...
  • Mortality during and following hospital admission among school-aged children: a cohort study 
    Ngari, Moses M.; Obiero, Christina; Mwangome, Martha K.; Nyaguara, Amek (Wellcome Open Research, 2021-01)
    Background: Far less is known about the reasons for hospitalization or mortality during and after hospitalization among school-aged children than among under-fives in low- and middle-income countries. This study aimed to ...
  • Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study 
    Irimu, Grace; Aluvaala, Jalemba; Malla, Lucas; Omoke, Sylvia; Ogero, Morris; Mbevi, George; Waiyego, Mary; Mwangi, Caroline; Were, Fred; Gathara, David; Agweyu, Ambrose; Akech, Samuel; English, Mike (BMJ Journals, 2021-05)
    Background: Most of the deaths among neonates in low-income and middle-income countries (LMICs) can be prevented through universal access to basic high-quality health services including essential facility-based inpatient ...
  • Pathways to Depression and Poor Quality of Life Among Adolescents in Western Kenya: Role of Anticipated HIV Stigma, HIV Risk Perception, and Sexual Behaviors 
    Kavulani Luseno, Winnie; Field, Samuel H.; Iritani, Bonita J.; Odongo, Fredrick S.; Kwaro, Daniel; Ombek Amek, Nyaguara; Rennie, Stuart (Springer Link, 2021-05)
    Depression is a major cause of disease burden and is linked to poor quality of life (QOL) among adolescents. We examined the roles of sexual behaviors, HIV risk perception, and anticipated HIV stigma on depressive ...
  • Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria 
    Thizy, Delphine; Toe, Lea Pare; Mbogo, Charles; Matoke-Muhia, Damaris; Alibu, Vincent Pius; Barnhill-Dilling, S. Kathleen; Chantler, Tracey; Chongwe, Gershom; Delborne, Jason; Kapiriri, Lydia; Nassonko Kavuma, Esther; Koloi-Keaikitse, Sethlomo; Kormos, Ana; Littler, Katherine; Lwetoijera, Dickson; Vargas de Moraes, Roberta; Mumba, Noni; Mutengu, Lilian; Mwichuli, Sylvia; Nabukenya, Silvia Elizabeth; Nakigudde, Janet; Ndebele, Paul; Ngara, Carolyne; Ochomo, Eric; Odiwuor Ondiek, Simon; Rivera, Stephany; Roberts, Aaron J.; Robinson, Benjamin; Sambakunsi, Rodrick; Saxena, Abha; Sykes, Naima; Tarimo, Brian B.; Tiffin, Nicki; Tountas, Karen H. (Gates Open Research, 2021-03)
    Gene drive research is progressing towards future field evaluation of modified mosquitoes for malaria control in sub-Saharan Africa. While many literature sources and guidance point to the inadequacy of individual informed ...
  • Respiratory syncytial virus seasonality in three epidemiological zones of Kenya 
    Rose, Erica Billig; Nyawanda, Bryan O.; Munywoki, Patrick K.; Murunga, Nickson; Bigogo, Godfrey M.; Otieno, Nancy A.; Onyango, Clayton; Chaves, Sandra S.; Verani, Jennifer R.; Emukule, Gideon O.; Widdowson, Marc-Alain; Nokes, D. James; Gerber, Susan I.; Langley, Gayle E. (Wiley Online, 2021-03)
    Understanding respiratory syncytial virus (RSV) circulation patterns is necessary to guide the timing of limited-duration interventions such as vaccines. We describe RSV circulation over multiple seasons in three distinct ...
  • A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa 
    Ndwiga, Leonard; Kimenyi, Kelvin M.; Wamae, Kevin; Osoti, Victor; Akinyi, Mercy; Omedo, Irene; Ishengoma, Deus S.; Duah-Quashie, Nancy; Andagalu, Ben; Ghansah, Anita; Amambua-Ngwa, Alfred; Tukwasibwe, Stephen; Tessema, Sofonias K.; Karema, Corine; Djimde, Abdoulaye A.; Dondorp, Arjen M.; Raman, Jaishree; Snow, Robert W.; Bejon, Philip; Ochola-Oyier, Lynette Isabella (Elsevier, 2021-08)
    Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 years ago has provided an invaluable tool ...
  • Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Kenyan blood donors 
    Uyoga, Sophie; Adetifa, Ifedayo; Karanja, Henry; Nyagwange, James; Tuju, James; Wanjiku, Perpetual; Aman, Rashid; Tsofa, Benjamin; Mwangangi, Mercy; Amoth, Patrick; Kadondi, Kasera; Ng'ang'a, Wangari; Rombo, Charles; Yegon, Christine; Kithi, Khamisi; Odhiambo, Elizabeth; Rotich, Thomas; Orgut, Irene; Kihara, Sammy; Otiende, Mark; Bottomley, Christian; Mupe, Zonia; Kagucia, Eunice; Gallagher, Katherine; Etyang, Anthony; Voller, Shirine; Gitonga, John; Mugo, Daisy; Agoti, Charles; Otieno, Edward; Ndwiga, Leonard; Lambe, Teresa; Wright, Daniel; Barasa, Edwine; Bejon, Philip; Ochola-Oyier, Lynette; Agweyu, Ambrose; G Scott, Anthony; Warimwe, George (2021-01-01)
    The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa is poorly described. The first case of SARS-CoV-2 in Kenya was reported on 12 March 2020, and an overwhelming number of cases and deaths ...

Search DSpace


Advanced Search

Browse

My Account