Browsing KEMRI Research Papers by Issue Date

Browsing KEMRI Research Papers by Issue Date

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  • Respiratory syncytial virus seasonality in three epidemiological zones of Kenya 
    Rose, Erica Billig; Nyawanda, Bryan O.; Munywoki, Patrick K.; Murunga, Nickson; Bigogo, Godfrey M.; Otieno, Nancy A.; Onyango, Clayton; Chaves, Sandra S.; Verani, Jennifer R.; Emukule, Gideon O.; Widdowson, Marc-Alain; Nokes, D. James; Gerber, Susan I.; Langley, Gayle E. (Wiley Online, 2021-03)
    Understanding respiratory syncytial virus (RSV) circulation patterns is necessary to guide the timing of limited-duration interventions such as vaccines. We describe RSV circulation over multiple seasons in three distinct ...
  • Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria 
    Thizy, Delphine; Toe, Lea Pare; Mbogo, Charles; Matoke-Muhia, Damaris; Alibu, Vincent Pius; Barnhill-Dilling, S. Kathleen; Chantler, Tracey; Chongwe, Gershom; Delborne, Jason; Kapiriri, Lydia; Nassonko Kavuma, Esther; Koloi-Keaikitse, Sethlomo; Kormos, Ana; Littler, Katherine; Lwetoijera, Dickson; Vargas de Moraes, Roberta; Mumba, Noni; Mutengu, Lilian; Mwichuli, Sylvia; Nabukenya, Silvia Elizabeth; Nakigudde, Janet; Ndebele, Paul; Ngara, Carolyne; Ochomo, Eric; Odiwuor Ondiek, Simon; Rivera, Stephany; Roberts, Aaron J.; Robinson, Benjamin; Sambakunsi, Rodrick; Saxena, Abha; Sykes, Naima; Tarimo, Brian B.; Tiffin, Nicki; Tountas, Karen H. (Gates Open Research, 2021-03)
    Gene drive research is progressing towards future field evaluation of modified mosquitoes for malaria control in sub-Saharan Africa. While many literature sources and guidance point to the inadequacy of individual informed ...
  • First do no harm: practitioners' ability to 'diagnose' system weaknesses and improve safety is a critical initial step in improving care quality 
    English, Mike; Ogola, Muthoni; Aluvaala, Jalemba; Gicheha, Edith; Irimu, Grace; McKnight, Jacob; Vincent, Charles A. (BMJ Journals, 2021-04)
    Healthcare systems across the world and especially those in low-resource settings (LRS) are under pressure and one of the first priorities must be to prevent any harm done while trying to deliver care. Health care workers, ...
  • Longitudinal-Survival Models for Case-Based Tuberculosis Progression 
    Kiplimo, Richard; Kosgei, Mathew; Mwangi, Ann; Onyango, Elizabeth; Ogero, Morris; Koske, Joseph (Frontiers, 2021-04)
    Introduction: Tuberculosis (TB) disease continues to be responsible for a high global burden with an estimated 10 million people falling ill each year and an estimated 1.45 million deaths. Widely carried out analyses to ...
  • A systematic review of the quality of conduct and reporting of survival analyses of tuberculosis outcomes in Africa 
    Ngari, Moses M.; Schmitz, Susanne; Maronga, Christopher; Mramba, Lazarus K.; Vaillant, Michel (BMC, 2021-04)
    Background: Survival analyses methods (SAMs) are central to analysing time-to-event outcomes. Appropriate application and reporting of such methods are important to ensure correct interpretation of the data. In this study, ...
  • Examining unit costs for COVID-19 case management in Kenya 
    Barasa, Edwine; Kairu, Angela; Ng'ang'a, Wangari; Maritim, Marybeth; Were, Vincent; Akech, Samuel; Mwangangi, Mercy (BMJ Journals, 2021-04)
    Introduction: We estimated unit costs for COVID-19 case management for patients with asymptomatic, mild-to-moderate, severe and critical COVID-19 disease in Kenya. Methods: We estimated per-day unit costs of COVID-19 ...
  • Health system responsiveness: a systematic evidence mapping review of the global literature 
    Khan, Gadija; Kagwanja, Nancy; Whyle, Eleanor; Gilson, Lucy; Molyneux, Sassy; Schaay, Nikki; Tsofa, Benjamin; Barasa, Edwine; Olivier, Jill (BMC, 2021-05)
    Background The World Health Organisation framed responsiveness, fair financing and equity as intrinsic goals of health systems. However, of the three, responsiveness received significantly less attention. Responsiveness ...
  • Pathways to Depression and Poor Quality of Life Among Adolescents in Western Kenya: Role of Anticipated HIV Stigma, HIV Risk Perception, and Sexual Behaviors 
    Kavulani Luseno, Winnie; Field, Samuel H.; Iritani, Bonita J.; Odongo, Fredrick S.; Kwaro, Daniel; Ombek Amek, Nyaguara; Rennie, Stuart (Springer Link, 2021-05)
    Depression is a major cause of disease burden and is linked to poor quality of life (QOL) among adolescents. We examined the roles of sexual behaviors, HIV risk perception, and anticipated HIV stigma on depressive ...
  • Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study 
    Irimu, Grace; Aluvaala, Jalemba; Malla, Lucas; Omoke, Sylvia; Ogero, Morris; Mbevi, George; Waiyego, Mary; Mwangi, Caroline; Were, Fred; Gathara, David; Agweyu, Ambrose; Akech, Samuel; English, Mike (BMJ Journals, 2021-05)
    Background: Most of the deaths among neonates in low-income and middle-income countries (LMICs) can be prevented through universal access to basic high-quality health services including essential facility-based inpatient ...
  • Clinical features of bacterial meningitis among hospitalised children in Kenya 
    Obiero, Christina W.; Mturi, Neema; Mwarumba, Salim; Ngari, Moses; Newton, Charles R.; van Hensbroek, Michaël Boele; Berkley, James A. (BMC, 2021-06)
    Background Diagnosing bacterial meningitis is essential to optimise the type and duration of antimicrobial therapy to limit mortality and sequelae. In sub-Saharan Africa, many public hospitals lack laboratory capacity, ...
  • A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa 
    Ndwiga, Leonard; Kimenyi, Kelvin M.; Wamae, Kevin; Osoti, Victor; Akinyi, Mercy; Omedo, Irene; Ishengoma, Deus S.; Duah-Quashie, Nancy; Andagalu, Ben; Ghansah, Anita; Amambua-Ngwa, Alfred; Tukwasibwe, Stephen; Tessema, Sofonias K.; Karema, Corine; Djimde, Abdoulaye A.; Dondorp, Arjen M.; Raman, Jaishree; Snow, Robert W.; Bejon, Philip; Ochola-Oyier, Lynette Isabella (Elsevier, 2021-08)
    Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 years ago has provided an invaluable tool ...
  • Using cross-species vaccination approaches to counter emerging infectious diseases 
    Warimwe, George M.; Francis, Michael J.; Bowden, Thomas A.; Thumbi, Samuel M.; Charleston, Bryan (Nature, 2021-12)
    Since the initial use of vaccination in the eighteenth century, our understanding of human and animal immunology has greatly advanced and a wide range of vaccine technologies and delivery systems have been developed. The ...

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