dc.contributor.author |
Nzivo, Mirriam Mbithe |
|
dc.date.accessioned |
2024-02-02T07:39:07Z |
|
dc.date.available |
2024-02-02T07:39:07Z |
|
dc.date.issued |
2019 |
|
dc.identifier.uri |
http://repository.kemri.go.ke:8080/xmlui/handle/123456789/341 |
|
dc.description.abstract |
The prevalence of Human Herpes Virus type 8 (HHV-8) is high in Sub-Saharan Africa
(36-60%) in the general population. The risk factors associated with HHV-8 range from
socio-demographic to geographic and behavioral characteristics. Documented studies on
HHV-8 in Kenya are few and data on its co-infection with Human Immunodeficiency
Virus (HIV) and syphilis is scanty. This study aimed at determining the prevalence of
HHV-8, associated risk factors and co-infection with HIV and syphilis among Female
Sex Workers (FSWs). A cross-sectional survey involving 268 participants was
conducted and blood samples screened for antibodies against HHV-8 using enzyme
linked Immunosorbent assay (ELISA). Infections by HIV and syphilis were tested using
parallel algorithm and one step Anti-TP test respectively. Socio-demographic data was
collected using a questionnaire administered by a health worker. The prevalence of
HHV-8 was 25% (67/268), HIV 16.4% (44/268) whereas syphilis accounted for 2.24%
(6/268). Of those infected with HHV-8, a co-infection of 12% (8/67) was recorded with
HIV and 3% (2/67) with syphilis. FSWs in marriage posed a significant risk to HHV-8
infection (OR 2.90; p=0.043). There was no significant association between HHV-8 and
HIV positivity (OR 0.62; p=0.257) or syphilis positivity (OR 1.52; p=0.636). HHV8/HIV co-infection was associated with increased age (OR 11.21; p=0.027) and syphilis
infection (OR 21.33; p=0.001). Lack of association between HHV-8 and HIV or syphilis
in this study shows that sexual mode does not play a significant role in HHV-8
transmission in this population. Continuous monitoring of HHV-8 infection and its
potential co-infections is recommended among FSWs and by extension the general
population. |
en_US |
dc.language.iso |
en |
en_US |
dc.subject |
Human Herpes Virus type 8 (HHV-8), Human Immunodeficiency Virus (HIV) and syphilis. |
en_US |
dc.title |
Human herpes virus types 8 and its coinfection with human immunodeficiency virus and treponema pallidum among female sex workers in Malindi,Kenya. |
en_US |
dc.type |
Thesis |
en_US |