| dc.contributor.author |
Gabriela Patten, Karen Malateste , Carolyn Bolton Moore , Nosisa Sipambo Limpho Mokone , Nanina Anderegg , Kara Wools-Kaloustian , Denna Michael Francesca Odhiambo Charles Kasozi , Sophie Desmonde Madeleine Amorissani-Folquet Valériane Leroy , Dewi Kumara Wati , Revathy Nallusamy Aarti Kinikar Du Tuan Quy , Marcel Yotebieng , Peter Vanes Ebasone , Patricia Lelo Jorge Pinto , Vanessa Rouzier Daisy Maria Machado , Nel Jason Haw , Nathan Ford; International epidemiology Databases to Evaluate AIDS collaboratio |
|
| dc.date.accessioned |
2026-03-31T12:15:26Z |
|
| dc.date.available |
2026-03-31T12:15:26Z |
|
| dc.date.issued |
2025-08 |
|
| dc.identifier.uri |
https://doi.org/10.1097/inf.0000000000004819 |
|
| dc.identifier.uri |
http://repository.kemri.go.ke:8080/xmlui/handle/123456789/1822 |
|
| dc.description.abstract |
Eligibility for antiretroviral therapy is no longer based on immune criteria. In a global cohort of 97,453 children, between 2005 and 2021, we observed large declines in CD4 measurement, from 51% to 12% among <5 seconds, and from 74% to 20% among those 5-14 years of age. Lack of CD4 testing may negatively affect clinical care and surveillance of severe immune suppression. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
The Peadiatric Infectious Disease Journal |
en_US |
| dc.subject |
CD4 cell count; advanced HIV disease; antiretroviral therapy; pediatric HIV; severe immune suppression. |
en_US |
| dc.title |
Global Trends in CD4 Measurement and Immunosuppression at ART Initiation Among Children With HIV |
en_US |
| dc.type |
Article |
en_US |