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Now showing items 1-20 of 340

HIV Type 1 Subtypes in Circulation in Northern Kenya

Samoeh Ashimosi Khamadi (AIDS Research and Human Retroviruses, 2005-10-05)

The genetic subtypes of HIV-1 circulating in northern Kenya have not been characterized. Here we report the partial sequencing and analysis of samples collected in the years 2003 and 2004 from 72 HIV-1-positive patients ...
HIV Type 1 Subtypes among STI Patients in Nairobi: A Genotypic Study Based on Partial pol Gene Sequencing

Wekesa Raphael Nyongesa (2006-12-05)

Circulating strains of human immunodeficiency virus (HIV) exhibit an extraordinary degree of genetic diversity and have been classified on the basis of relationships into distinct lineages called groups, types, subtypes, ...
Determinants of delivery by skilled birth atendants among pregnant women in Makueni County, Kenya

HARUN M KIMANI; Carey Farquhar, Peter Wanzala, and Zipporah Ng'ang'a (Public Health Research, 2015)

Background: Skilled birth attendants (SBAs) can improve outcomes during delivery and postpartum by detecting and managing early complications of pregnancy and labor. The objective of this study was to determine factors ...
RANTES Gene Polymorphisms Associated with HIV-1 Infections in Kenyan Population

SHEM PETER MUTUA MUTUIRU; Helen L. Kutima, Lamech M. Mwapagha, James K. Munyao, Anthony Kebira Nyamache, Irene Wanjiru, Samoel A. Khamadi (Hindawi Publishing CorporationDisease Markers, 2016)

Previous studies have reported that two single nucleotide polymorphisms (SNPs) in the RANTES gene promoter region, -403G/A and -28C/G, are associated with a slower rate of decline in CD4+ T cell count. In addition, as a ...
Assessing feasibility of using Oral Fluid assay as Alternative method in the Detection of Rubella Virus-Specific IgM Antibodies in routine disease surveillance Programme in Kenya

ROSE CHELANGAT; Kombich Janet and OngusJuliette R (Advances in Life Science and Technology, 2016)

Background: The WHO recommends the inclusion of rubella testing in the measles surveillance system. Laboratory diagnosis of measles and rubella virus infection is achieved by serological assay for specific IgM from a ...
Mutations in the “a” Determinant Region of Hepatitis B Virus Genotype A among Voluntary Kenyan Blood Donors

EDINAH KEMUNTO NYAIRO; Zipporah Ng'ang'a, James Kimotho, Samoel A. Khamadi, Lihana Raphael (Journal of Biology, Agriculture and Healthcare, 2016)

Occurrence of mutations within the major antigenic alpha determinant region of hepatitis B surface antigen (HBsAg can alter HBV antigenicity resulting in failures in diagnosis, vaccine and hepatitis B immunoglobulin therapy. ...
The Potential for DPPIV/CD26 usage as a surrogate marker for Antiretroviral Therapy Efficacy in HIV Infected populations

AYUB KIPROTICH MAINA; Joseph K Mbugua, Adriana Trajtman, Yoav Keynan, Robert W Omange, Annie Panikulam, Rachel Musoke, James Kimotho, Missiani Ochwoto, Daniel Kariuki, Elijah M Songok (African Journal of Pharmacology and Therapeutics, 2016)

Background: Human Immunodeficiency Virus (HIV) viral load and CD4+ cell counts are the most commonly usedmarkers for monitoring efficacy of anti-retroviral therapy (ART) in HIV infected individuals. The high cost of viralload ...
Factors Associated with Cervical Cancer Screening Uptake in Naivasha District, Kenya

MBATIA, SERAH F. W.; Kenneth Ngure, Erastus Muniu, Sophie Musenjeri (Journal of Health, Medicine and Nursing, 2016)

The objective was to determine and explore factors associated with cervical cancer screening uptake among women attending the family planning clinic at a public hospital in Naivasha District. A concurrent triangulation ...
ASSESSING FACTORS ASSOCIATED WITH OBSERVED LEVELS OF ADHERENCE TO ANTIRABIES PEP VACCINE AMONG ANIMAL BITE VICTIMS IN MACHAKOS LEVEL FIVE HOSPITAL

GICHOHI, ALICE NJERI; Dr. Yeri Kombe, Dr.Peter Mwaniki, Dr.Joseph Mutahi, Anne G Macharia (American Journal of Health, Medicine and Nursing Practice, 2016)

Purpose: The purpose of this study was to determine factors associated with observed levels of adherence to ant rabies PEP vaccine among animal bite victims in Machakos level five hospital. Methodology: The study used ...
Development of a Loop Mediated Isothermal Amplification for Diagnosis of Ascaris lumbricoides in Fecal Samples

SHIRAHO, ESTHER ANDIA; Agola L. Eric, Ibrahim N. Mwangi, Geoffrey M. Maina, Joseph M. Kinuthia, Martin W. Mutuku, Robert M. Mugambi, Jackson M. Mwandi, Gerald M. Mkoji (Journal of Parasitology Research, 2016)

Ascaris lumbricoides is a nematode parasite that causes the common tropical infection ascariasis in humans. It is also considered among the neglected tropical diseases. Diagnosis relies mainly on microscopy-based methods ...
Substance abuse among college youth in one of the largest transit hub in Machakos County Kenya; a cross sectional study on prevalence and associated factors

KERUBO, ASANYO LILY; Musa Otieno Ngayo, Joseph Gikunju , Mohammed Karama (Journal of Health, Medicine and Nursing, 2016)

BACKGROUND: Substance abuse among college students is a growing problem confronting Kenya today. Substance abuse in this population predicts substance related problems in later life. This study is a buildup of limited ...
Factors Associated With Nutritional Status among Children with Visceral Leishmaniasis (Vl) Attending Kacheliba Subcounty Hospital, West Pokot County, Kenya

NAMULEN, ANN IRUATA; Simon Karanja, Yeri Kombe (Journal of Health Medicine and Nursing, 2016)

Visceral Leishmaniasis (VL) causes considerable morbidity and mortality in Kenya. However, data on the factors associated with nutritional status among children aged 5-12 years at Kacheliba Sub County Hospital is nonexistent. ...
Molecular characterization of human coronaviruses and their circulation dynamics in Kenya, 2009–2012

LENATA ANASTACIA SIPULWA; Juliette R. Ongus, Rodney L. Coldren, and Wallace D. Bulimo (Virology Journal, 2016-02)

Background Human Coronaviruses (HCoV) are a common cause of respiratory illnesses and are responsible for considerable morbidity and hospitalization across all age groups especially in individuals with compromised immunity. ...
In vitro and in vivo efficacy of combination therapy using Allium sativum and Aloe secundiflora against Leishmania major infected BALB/c mice

KITUYI CHRISTINE N.; Ndeti Cosmas Muia, Maina Geoffrey, Mongâ, Samuel, Ingonga Johnstone, Nyambati Venny, Anjili Christopher Omukhango (International Journal of Fauna and Biological Studies, 2016-02)

Allium sativum and Aloe secundiflora water extracts have antileishmanial activities. In the present study, the efficacy of combination therapy using A. sativum and A. secundiflora against L. major was studied both ...
Serotypes and Antimicrobial Susceptibility Patterns of Nasopharyngeal Pneumococci Isolated from HIV-Infected Children in Selected Pediatric Clinics in Nairobi, Kenya

CATHERINE N. MWANGI; Gunturu Revathi, Anne W. Muigai, Samuel Kariuki (Open Journal of Medical Microbiology, 2016-03)

Background: Streptococcus pneumoniae (pneumococcus) is one of the most frequent causes of bacterial infection in children and is a leading cause of otitis, sinusitis, pneumonia, and meningitis worldwide. Nasopharyngeal ...
A retrospective evaluation of proficiency testing, and rapid HIV test kits stock-outs among HTC facilities within Nairobi county

IRERI MUGAMBI EDWARD; MW Mutugi, NL Muthami, M Kiptoo, EM Songok (East African Medical Journal, 2016-03)

Background: Proficiency testing (PT) has been implemented as a form of External Quality Assurance (EQA) by the National HIV Reference Laboratory in Kenya since 2007 in order to monitor and improve on the quality of HIV ...
Efficacy of combination therapy using extracts of Aloe secundiflora Eng L and Callistemon citrinus William C. in Leishmania major infected BALB/c mice

NDETI, COSMAS MUIA; C. Kituyi, M. Ndirangu, J. Ingonga, M. L. Chimbevo, J. O. Ochieng, M. Barasa, G. Kinuthia, E. M. Maina, V. C. S. Nyambati, C. O. Anjili (East African Medical Journal, 2016-03)

Background: Leishmania major causes cutaneous leishmaniasis which leads to painful skin sores in humans. In the current study, efficacy of combination therapy of A. secundiflora and C. citrinus against L. major infected ...
Methylene blue inhibits lumefantrine-resistant Plasmodium berghei

MWANGI VICTOR IRUNGU; Ruth Mwende Mumo, Daniel Muthui Kiboi, Sabah Ahmed Omar, Zipporah Waithera Ng’ang’a, Hastings Suba Ozwara (Journal of Infection in Developing Countries, 2016-06)

Introduction: Chemotherapy still is the most effective way to control malaria, a major public health problem in sub-Saharan Africa. The large-scale use of the combination therapy artemether-lumefantrine for malaria treatment ...
A quantitative study on the determinants of utilization of skilled birth attendance, Bamba division, Kilifi

MWINYIKIONE, SOPHIA WAITHERA; Yeri Kombe, Drusilla Makworo (International Journal of Community Medicine and Public Health, 2016-06)

Background: Improving maternal health by three quarters is the fifth millennium development goal that is set to be achieved through the provision of skilled attendance during delivery. However, the proportion of Skilled ...
The Effect of Human Immunodeficiency Virus Prevention and Reproductive Health Text Messages on Human Immunodeficiency Virus Testing Among Young Women in Rural Kenya

NJUGUNA, NJAMBI; Ngure, Kenneth; Mugo, Nelly; Sambu, Carrole; Sianyo, Christopher; Gakuo, Stephen; Irungu, Elizabeth; Baeten, Jared; Heffron, Renee (Journal of American Sexually Transmitted Diseases Assocciation, 2016-06)

Background More than half of human immunodeficiency virus (HIV)–infected individuals in Kenya are unaware of their status, and young women carry a disproportionate burden of incident HIV infections. We sought to determine ...

Now showing items 1-20 of 340

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