Infections with intestinal parasites are a major public health problem in children in developing
countries like Kenya. School-going children are considered more vulnerable to intestinal parasitic
infections and thus ...
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the causative agent for
COVID-19, is a positive-sense enveloped RNA virus belonging to the Betacoronavirus genus
and is approximately 30 kilobases long. ...
MUSEMBI MICHAEL MUTETI(KEMRI Graduate School, 2025)
Sickle cell anaemia (SCA) is a severe monogenic disorder that results in abnormal hemoglobin
with sub-Saharan Africa bearing 75% of the global burden. Blood transfusion is an integral part
of patient management and the ...
Effective viral load (VL) sample management is critical for reliable laboratory
monitoring, timely clinical decision-making, and improved patient outcomes. Viral
load testing is essential for effective HIV management; ...
Biomphalaria pfeifferi, a predominantly self-fertilizing freshwater snail, is the world’s most
important intermediate host for transmission of Schistosoma mansoni, one of the causative agents
of schistosomiasis, a ...
Pneumocystis jirovecii pneumonia (PJP) is an underdiagnosed opportunistic infection,
particularly in TB-endemic regions where clinical manifestations overlap. There are still
significant challenges to overcome, despite ...
Human immunodeficiency virus (HIV) infection leads to progressive immune system decline,
often requiring lifelong treatment to control viral replication and prevent complications. The use
of combination antiretroviral ...
BACKGROUND: Decidual macrophages are essential during pregnancy playing the
most critical role in tolerance, tissue priming, parturition, and postpartum recapability.
Change in the placental microenvironment leading ...
PHILIP MUTISYA NZIOKI(KEMRI Graduate School, 2025)
This study investigated factors influencing adherence to combined antiretroviral therapy
(cART) among HIV-infected adolescents in Machakos County, Kenya, using a mixed methods approach. Quantitative data from structured ...
Schistosomiasis is a disease of global public health importance among populations
residing in Schistosoma-infection prone areas. Global interventions have not succeeded
yet in control, elimination nor eradication of ...
The global prevalence of diseases is heavily impacted by the consumption of unsafe drinking
water. In Low- and Middle-Income Countries (LMIC), bottled drinking water is among the
fastest growing options for seemingly ...
Campylobacter spp. are significant global contributors to food poisoning. These
bacteria harbor virulence and resistance genes that play crucial roles in invasion and
antibiotic resistance. Understanding the molecular ...
The persistence of HIV/AIDS as a significant global health concern is particularly pronounced in developing nations, where 35 million people are affected, with 70% residing in sub-Saharan Africa. Annually, 2.1 million new ...
Genital chlamydia, caused by diverse C. trachomatis strains, is largely asymptomatic but can
also present with pelvic discharge, itchy vulva or lower abdominal pain. We aimed to identify
genital chlamydia strains amongst ...
The World Health Organization has also suggested the application of pre-exposure prophylaxis (PrEP) as a strategic public health HIV infection prevention intervention among highrisk individuals. Awareness and utilization ...
Malaria remains a major public health problem globally, despite significant success in malaria control programs in the past. Long lasting insecticidal nets (LLINs) are the major vector control method used to prevent malaria ...
Dengue virus (DENV) and Yellow fever virus (YFV) are RNA viruses belonging to
the genus Flavivirus and family Flaviviridae. Their emergence and re-emergence have
become crucial public health problems, especially in ...
Dengue is a public health concern because it is a viral hemorrhagic disease spread by the Aedes aegypti mosquito vector. The disease is caused by the dengue virus (DENV) which has four different serotypes (DENV 1-4). Dengue ...
Schistosomiasis is a disease of global public health importance among populations residing in Schistosoma-infection prone areas. Global interventions have not succeeded yet in control, elimination nor eradication of the ...
This study investigated factors influencing adherence to combined antiretroviral therapy (cART) among HIV-infected adolescents in Machakos County, Kenya, using a mixedmethods approach. Quantitative data from structured ...